Protein Info for HMPREF1181_RS12560 in Bacteroides stercoris CC31F

Annotation: putative transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 554 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 37 to 57 (21 residues), see Phobius details amino acids 69 to 88 (20 residues), see Phobius details amino acids 100 to 119 (20 residues), see Phobius details amino acids 158 to 180 (23 residues), see Phobius details amino acids 375 to 395 (21 residues), see Phobius details amino acids 404 to 424 (21 residues), see Phobius details amino acids 436 to 456 (21 residues), see Phobius details amino acids 468 to 490 (23 residues), see Phobius details amino acids 497 to 517 (21 residues), see Phobius details amino acids 529 to 553 (25 residues), see Phobius details PF06826: Asp-Al_Ex" amino acids 20 to 181 (162 residues), 137.1 bits, see alignment E=5.3e-44 amino acids 377 to 549 (173 residues), 156 bits, see alignment E=8e-50 TIGR01625: AspT/YidE/YbjL antiporter duplication domain" amino acids 25 to 168 (144 residues), 123.1 bits, see alignment E=4.2e-40 amino acids 382 to 536 (155 residues), 160.1 bits, see alignment E=1.8e-51 PF02080: TrkA_C" amino acids 299 to 364 (66 residues), 45.4 bits, see alignment E=5.8e-16

Best Hits

Swiss-Prot: 90% identical to Y1818_BACFR: Uncharacterized transporter BF1818 (BF1818) from Bacteroides fragilis (strain YCH46)

KEGG orthology group: None (inferred from 95% identity to bhl:Bache_2732)

Predicted SEED Role

"putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (554 amino acids)

>HMPREF1181_RS12560 putative transporter (Bacteroides stercoris CC31F)
MEWLYSLFVEHSALQAVVVLSLISAIGLGLGKIHICGISLGVTFVFFAGILAGHFGLSID
PQMLNYAESFGLIIFVYALGLQVGPGFFSSFRKGGVQLNMLALGVVLLGTLMTVLGSYTL
NISLPDMVGILCGATTNTPALGAAQQTLKQMGLEASTPALGCAVAYPLGVVGVIFAVLII
RKALARKEDLELKEKDDANKTYIAAFQVHNPAIFDKSIKEIGGLNYPKFVISRLWRDGNV
SIPTSEKIIREGDRLLVVTSEKYAPALTVLFGEQEHTDWNKEDIDWNAIDSQLISQRIVV
TRPELNGKKLGALHLRNHYGINISRVYRSGVQLLATAELTLQLGDRLTVVGEAAAIQNVE
KVLGNAIKSLKEPNLVAVFIGIILGLALGAIPISLPGISAPVKLGLAGGPIIVGILIGTF
GPRMHMITYTTRSANLMLRALGLSLYLACLGLDAGAHFFDTVFRPEGLLWIAAGFVLTVV
PVLIVGVVAFKWMKVDFGSMAGMLCGSMANPMALNYANDTIPGDNPSVAYATVYPMCMFL
RVIIAQVLLMFLLN