Protein Info for HMPREF1181_RS12455 in Bacteroides stercoris CC31F

Annotation: cytochrome d ubiquinol oxidase subunit II

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 383 transmembrane" amino acids 12 to 38 (27 residues), see Phobius details amino acids 58 to 78 (21 residues), see Phobius details amino acids 84 to 105 (22 residues), see Phobius details amino acids 118 to 141 (24 residues), see Phobius details amino acids 180 to 199 (20 residues), see Phobius details amino acids 218 to 239 (22 residues), see Phobius details amino acids 260 to 281 (22 residues), see Phobius details amino acids 293 to 313 (21 residues), see Phobius details amino acids 342 to 361 (20 residues), see Phobius details PF02322: Cyt_bd_oxida_II" amino acids 7 to 364 (358 residues), 232 bits, see alignment E=5.2e-73

Best Hits

KEGG orthology group: K00426, cytochrome bd-I oxidase subunit II [EC: 1.10.3.-] (inferred from 90% identity to bhl:Bache_2706)

Predicted SEED Role

"Cytochrome d ubiquinol oxidase subunit II (EC 1.10.3.-)" in subsystem Bacterial RNA-metabolizing Zn-dependent hydrolases or Conserved gene cluster associated with Met-tRNA formyltransferase or Terminal cytochrome d ubiquinol oxidases or Terminal cytochrome oxidases (EC 1.10.3.-)

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (383 amino acids)

>HMPREF1181_RS12455 cytochrome d ubiquinol oxidase subunit II (Bacteroides stercoris CC31F)
MNTYIFLQHYWWFIVSLLGAILVFLLFVQGGNSLIFCLGKTEEQRKMIINSTGRKWEFTF
TTLVTFGGAFFASFPLFYSTSFGGAYWLWMIILFTFVLQAVSYEFQSKAGNLLGKTTYRA
FLVINGVVGPVLLGGAVATFFTGSEFYINKGNIADTVMPVISSWANAGHGLDALLNPWNV
VLGLAVFFLARILGALYFINNIGDADLVKRCRRALWGNTGLFLVFFLAFVIRTLLAEGYA
VNPETGEVFMEPYKYLTNFIEMPVVLLVFLIGVLAVLWGIVRTVWKPSFDKGIWFAGAGT
VLTVLALLLVAGYNNTAYYPSTADLQSSLTLANSCSSQFTLRVMAYVSVLVPFVLAYIFY
AWRSIDRKKIDAEEMQDEKGHAY