Protein Info for HMPREF1181_RS11845 in Bacteroides stercoris CC31F
Annotation: ABC transporter substrate-binding protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K02016, iron complex transport system substrate-binding protein (inferred from 84% identity to bhl:Bache_1758)Predicted SEED Role
"Vitamin B12 ABC transporter, B12-binding component BtuF" in subsystem Coenzyme B12 biosynthesis
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (378 amino acids)
>HMPREF1181_RS11845 ABC transporter substrate-binding protein (Bacteroides stercoris CC31F) MRKVTLLFLMLTLVLFLSACSGKDKTVSVFISGDTIPLRYADNLTLVSYPGYTIATLRNP WDTLKTLHTYILVPASQPLPAHLPEGTIVRTPLRKSVIYSSVHCSLMDKLGAAGCIGGVC DLKYIKLPVIQDGYRNGTVTDCGDGMNPDMEKIIDLHPDAILLSPFENSGGYGRVEKLNI PIIECADYMETSALGRAEWMRFYGLLFGVVSKADSLFAEVDSCYNQLRKRASLSSSSLSI VSELKSGSAWYVPGGCSTIGRLFNDACGRYAFAEDKHSGSIPLAFETVFDKAGDADVWTI KYNRDRDMTYSDLKADYIGYTGFKAFKTRNIYGCNTAKVPFYEETPFRPDYLLSDLIQIL HPEIGDLGGLRYFCKLNE