Protein Info for HMPREF1181_RS11815 in Bacteroides stercoris CC31F

Annotation: chloride channel protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 525 transmembrane" amino acids 28 to 54 (27 residues), see Phobius details amino acids 66 to 88 (23 residues), see Phobius details amino acids 119 to 136 (18 residues), see Phobius details amino acids 167 to 191 (25 residues), see Phobius details amino acids 203 to 224 (22 residues), see Phobius details amino acids 244 to 265 (22 residues), see Phobius details amino acids 277 to 297 (21 residues), see Phobius details amino acids 317 to 337 (21 residues), see Phobius details amino acids 345 to 367 (23 residues), see Phobius details amino acids 373 to 399 (27 residues), see Phobius details amino acids 406 to 423 (18 residues), see Phobius details PF00654: Voltage_CLC" amino acids 81 to 423 (343 residues), 247.7 bits, see alignment E=2e-77 PF02080: TrkA_C" amino acids 454 to 517 (64 residues), 41.5 bits, see alignment E=9.8e-15

Best Hits

KEGG orthology group: None (inferred from 72% identity to bfs:BF1190)

Predicted SEED Role

"Voltage-gated chloride channel family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (525 amino acids)

>HMPREF1181_RS11815 chloride channel protein (Bacteroides stercoris CC31F)
MRFFQKIKNWKTVRGWHIWKLKLVDARLYFVSMIVGLLTGLIAVCYHYLLYFLLHIRSDF
FASRPAWYWHILLFLLFWGILMFVSFLVGRMPLISGGGIPQTRGVINGRITYKHPFVELV
SKFAGGILSVAAGLSLGREGPSVQIGSYIGSLVSRWTHILQGERKQLLAAGAGAGLAAAF
AAPLASSLIVIESIERFDAPKTAITTLLAGVVAGAVAGLVFPVNPYHLIEVSEPVLTFLV
RMKYFLLLAVIISIAGKIYSVLMISFKRVYSKVKSPVYIKMFYLVLVAYIISLMQVNLTG
GGEQFLLQQAQNGSTEIMWVLAVMLLHFGFSVCSVSSGLPGGNFIPTLVTGGLLGQLVGL
VAVKYGIIEPPNITYVMLISMSAFLVAIERTPLTAIVLITEITGHFEVFYPSVVVGGLTY
YFTELLQMKSFNVILYEDMINSPDFREENRYTLSVEVMTGSYFDGKAVSELSLPERCVII
NVHRDGKNLVPAETSLIPGDQVQIEMDSQDIEKLYEPLVSMANIY