Protein Info for HMPREF1181_RS11255 in Bacteroides stercoris CC31F

Annotation: anaerobic C4-dicarboxylate transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 436 transmembrane" amino acids 6 to 38 (33 residues), see Phobius details amino acids 49 to 71 (23 residues), see Phobius details amino acids 90 to 116 (27 residues), see Phobius details amino acids 132 to 158 (27 residues), see Phobius details amino acids 167 to 186 (20 residues), see Phobius details amino acids 224 to 244 (21 residues), see Phobius details amino acids 260 to 280 (21 residues), see Phobius details amino acids 292 to 311 (20 residues), see Phobius details amino acids 332 to 350 (19 residues), see Phobius details amino acids 358 to 382 (25 residues), see Phobius details amino acids 414 to 433 (20 residues), see Phobius details TIGR00770: transporter, anaerobic C4-dicarboxylate uptake (Dcu) family" amino acids 4 to 433 (430 residues), 540.2 bits, see alignment E=2e-166 PF03605: DcuA_DcuB" amino acids 4 to 369 (366 residues), 513.7 bits, see alignment E=1.4e-158

Best Hits

Swiss-Prot: 56% identical to DCUB_HAEIN: Anaerobic C4-dicarboxylate transporter DcuB (dcuB) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K07791, anaerobic C4-dicarboxylate transporter DcuA (inferred from 92% identity to bfs:BF4038)

Predicted SEED Role

"Anaerobic C4-dicarboxylate transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (436 amino acids)

>HMPREF1181_RS11255 anaerobic C4-dicarboxylate transporter (Bacteroides stercoris CC31F)
MVLQLLFVLTAIIIGARLGGIGLGVMGGVGLGILTFVFGLQPTAPPIDVMLMIAAVISAA
SCMQAAGGLDYMVKLAEKLLRKNPSQVTILSPIVTYLFTFVAGTGHVAYSVLPVIAEVAT
ETKIRPERPLGIAVIASQQAITASPISAATVALLGLLAGFDITLFDILKITIPATILGVL
VGALCSMRVGKELIDDPEYQKRMAEGYFDGKKVKIDDVTNKRHAMISVLIFILATAFIVL
FGSFEGMRPSFLIDGKTVSLGMSAIIEIIMLSAAALILLVTKTDGIKATQGSVFPAGMQA
VIAIFGIAWMGDTFLNGNMAQLTASIEGIVRQMPWLFGIALFVMSILLYSQAATVRALVP
LGIALGISPYMLIAMFPAVNGYFFIPNYPTVVAAINFDRTGTTRIGKYILNHSFMMPGIV
STAVAIALGLLFIQFF