Protein Info for HMPREF1181_RS10740 in Bacteroides stercoris CC31F

Annotation: sigma-70 family RNA polymerase sigma factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 203 TIGR02937: RNA polymerase sigma factor, sigma-70 family" amino acids 36 to 192 (157 residues), 92.2 bits, see alignment E=1.4e-30 PF04542: Sigma70_r2" amino acids 41 to 107 (67 residues), 44.2 bits, see alignment E=1.4e-15 PF08281: Sigma70_r4_2" amino acids 138 to 186 (49 residues), 45.9 bits, see alignment E=3.6e-16

Best Hits

KEGG orthology group: K03088, RNA polymerase sigma-70 factor, ECF subfamily (inferred from 92% identity to bhl:Bache_1987)

Predicted SEED Role

"RNA polymerase ECF-type sigma factor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (203 amino acids)

>HMPREF1181_RS10740 sigma-70 family RNA polymerase sigma factor (Bacteroides stercoris CC31F)
MLRLTNKRREEASVKRALTLENEIELIEGCRAGKDSARKELYTLYSKQMLAVCYRYTGDM
DAAHDVLHDGFIKIFTRFTFRGECALGTWVTRVMVTQAIDYLRRKHRFSQLVVNEEQLPD
VQDEASIAESGSGLSEEVLMAFVAELPDGCRTVFNLYVFEEKSHKEIAELLHIKEHSSTS
QLHRAKCMLAKRIKEYTEYERKR