Protein Info for HMPREF1181_RS09480 in Bacteroides stercoris CC31F

Annotation: GTPase HflX

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 419 TIGR03156: GTP-binding protein HflX" amino acids 14 to 393 (380 residues), 411 bits, see alignment E=3.6e-127 PF13167: GTP-bdg_N" amino acids 31 to 123 (93 residues), 110.8 bits, see alignment E=8.1e-36 PF16360: GTP-bdg_M" amino acids 125 to 212 (88 residues), 101.7 bits, see alignment E=5.3e-33 PF01926: MMR_HSR1" amino acids 217 to 335 (119 residues), 76.8 bits, see alignment E=2.9e-25

Best Hits

Swiss-Prot: 60% identical to HFLX_FLAPJ: GTPase HflX (hflX) from Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511)

KEGG orthology group: K03665, GTP-binding protein HflX (inferred from 95% identity to bhl:Bache_1193)

Predicted SEED Role

"GTP-binding protein HflX" in subsystem Hfl operon or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (419 amino acids)

>HMPREF1181_RS09480 GTPase HflX (Bacteroides stercoris CC31F)
MKEFVISEAQVETAVLVGLITKTQDERKTNEYLDELAFLAETAGAEVVKRFTQKLDQANS
VTYVGKGKLEEIKEYIRSEEEAEREIGMVIFDDELSAKQIRNIEAELKIKILDRTSLILD
IFAMRAQTANAKTQVELAQYKYMLPRLQRLWTHLERQGGGSGAGGGKGSVGLRGPGETQL
EMDRRIILNRMSLLKDRLAEIDKQKATQRKNRGRLIRVALVGYTNVGKSTLMTLLSKSEV
FAENKLFATLDTTVRKVIIENLPFLLSDTVGFIRKLPTDLVDSFKSTLDEVREADLLLHI
VDISHPDFEEQIEVVNKTLADIGASGKPMILVFNKIDAYTYVAKADDDLTPRTKENLTLE
ELMKTWMAKLEDNCLFISARERINVEELKSVVYRRVKELHVQKYPYNDFLYQTYDEEEV