Protein Info for HMPREF1181_RS09305 in Bacteroides stercoris CC31F

Annotation: PD40 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1088 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF07676: PD40" amino acids 56 to 91 (36 residues), 47.6 bits, see alignment (E = 2.3e-16) amino acids 100 to 124 (25 residues), 13.4 bits, see alignment (E = 1.2e-05) amino acids 210 to 244 (35 residues), 35.2 bits, see alignment (E = 1.7e-12) amino acids 310 to 335 (26 residues), 16.7 bits, see alignment (E = 1.1e-06) amino acids 348 to 382 (35 residues), 32 bits, see alignment (E = 1.9e-11) amino acids 617 to 651 (35 residues), 13.4 bits, see alignment (E = 1.2e-05) PF14684: Tricorn_C1" amino acids 715 to 782 (68 residues), 92.2 bits, see alignment 3.5e-30 PF03572: Peptidase_S41" amino acids 905 to 1060 (156 residues), 82.7 bits, see alignment E=4.6e-27

Best Hits

KEGG orthology group: None (inferred from 81% identity to bhl:Bache_1230)

Predicted SEED Role

"putative Tricorn-like protease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1088 amino acids)

>HMPREF1181_RS09305 PD40 domain-containing protein (Bacteroides stercoris CC31F)
MKKIFAYLTLGFTTLTTYAATPLWMRDIQISPDGTEIVFCYKGDIYKVSAKGGTATQLTT
QESYESSPVWSPDGKQIAFASDRQGNFDVFVMPSNGGAAQRLTTNSAGEIPSAFTPDGKY
ILFSAAIQDPAGSALFPSPAMTELYKVPATGGRTEQVLGTPAEALCFDKTGDMFFYQDQK
GFEDQWRKHHTSSITRDIWMYDCRTEKHTNLTRHAGEDRNPVLSPDGQTLYFLSERNGGS
FNVYSLQPAHPEAVKAVSSFKTHPVRFLSISGNGTLCYGYDGEIYTQQDGAAPQKVQIEI
IRDDRPDTARLTFTNGATSATVSPDGKQVAFIARGEVFVTSADYATTKQITHTPAGESGL
SFAPDNRTLAYASERNGNWQLYLAKIVRKEDPNFPNATIVEEEALLPSATVERAFPQFSP
DGKELAFIEDRTRLMVVNLDTKKVRQITDGSTWYSTDGGFDYAWSPDGKWFTLEFIGNRH
DPYSDIGLVSAQGNSPIINLTNSGYMSGSPRFALDGNAILFKTERYGMRAHASWGSQDDA
MLVFLNQDAYDKYCLSKENYELRKELEAEQKKAQSKDTAKGKKGSKKDAGQEKAADDDKA
QVKDITVELKNMEDRMVRLTPNSSDMGSVIISKDGETLYYFAAFEGGYDLWKMDLRKKDT
RLLHKMDAGWASMEMDKDGKNLFLLGGKTMQKMNMASDELKPVTYRAQAKMDLAAEREYM
FNHVYKQQKKRFYNTDMHGVDWDAMSAAYRKFLPHIDNNYDFAELLSEWLGELNVSHTGG
RYYASGQSEPTASLGLLFDWNYRDKGMRIAEVIEKGPFDNASTKAKAGIIIEKIDGTEIT
PEMDYYTLLNDKAKKKTLVSLYNPQTKERWEEVVIPISGSALNTLLYTRWVKQRAADVDR
WSGGRLGYVHIESMGDDSFRSVYSDILGKYNNREGIVIDTRFNGGGRLHEDIEILFSGQK
YFTQVVRGREACDMPSRRWNKPSIMVTCEANYSNAHGTPWVYRHRNIGKLVGMPVPGTMT
SVSWERLQDPSLVFGIPVVGYRLPDGSYLENSQLEPDIKVANSPETIVKGEDTQLKVAVE
ELLKELDK