Protein Info for HMPREF1181_RS08235 in Bacteroides stercoris CC31F

Annotation: MotA/TolQ/ExbB proton channel family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 269 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 74 to 95 (22 residues), see Phobius details amino acids 172 to 196 (25 residues), see Phobius details amino acids 216 to 238 (23 residues), see Phobius details PF01618: MotA_ExbB" amino acids 131 to 250 (120 residues), 91 bits, see alignment E=2.7e-30

Best Hits

KEGG orthology group: K03561, biopolymer transport protein ExbB (inferred from 97% identity to bhl:Bache_3305)

Predicted SEED Role

"Ferric siderophore transport system, biopolymer transport protein ExbB" in subsystem Campylobacter Iron Metabolism or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (269 amino acids)

>HMPREF1181_RS08235 MotA/TolQ/ExbB proton channel family protein (Bacteroides stercoris CC31F)
MKKLFAIVAVMGVLTFGSTQLAQAQDAPAAEQTEQAAPAAQAAPADEAAAPVVAEEGGIH
KEIKTKFIEGTASFMSLVAIALVIGLAFCIERIIYLSLAEINTKKFIAAIEAALEKGDVE
AAKDIARNTRGPIASIYYQGLMRIDQGIDVVEKSVVSYGGVQAGYLEKGCSWITLFIAMA
PSLGFLGTVIGMVQAFDKIQQVGDISPTVVAGGMKVALITTIFGLIVALILQVFYNYILS
KIEALTSEMEDSSISLLDMVIKYDLKYKK