Protein Info for HMPREF1181_RS08035 in Bacteroides stercoris CC31F

Annotation: RNA degradosome polyphosphate kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 696 TIGR03705: polyphosphate kinase 1" amino acids 4 to 685 (682 residues), 693.6 bits, see alignment E=1.5e-212 PF13089: PP_kinase_N" amino acids 5 to 110 (106 residues), 109.6 bits, see alignment E=2.4e-35 PF02503: PP_kinase" amino acids 120 to 308 (189 residues), 166.2 bits, see alignment E=1.7e-52 PF17941: PP_kinase_C_1" amino acids 336 to 502 (167 residues), 215.3 bits, see alignment E=1.1e-67 PF13091: PLDc_2" amino acids 372 to 496 (125 residues), 28.5 bits, see alignment E=2.9e-10 PF13090: PP_kinase_C" amino acids 509 to 680 (172 residues), 215 bits, see alignment E=1.3e-67

Best Hits

KEGG orthology group: K00937, polyphosphate kinase [EC: 2.7.4.1] (inferred from 88% identity to bhl:Bache_3272)

Predicted SEED Role

"Polyphosphate kinase (EC 2.7.4.1)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism or Purine conversions (EC 2.7.4.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.4.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (696 amino acids)

>HMPREF1181_RS08035 RNA degradosome polyphosphate kinase (Bacteroides stercoris CC31F)
MESRYFKRDISWLSFNYRVLLEAEDDTLPLYERINFISIYSSNLEEFYKIRVADHKAIAT
GAAHSDEESVQSAMQLVSEINEEVNRQLEERIRIYEQKILPALRQQHIIFYQSRNVEPFH
KEFLRSFFREEIFPYLSPVPVSKDKVISFLRDNRLYLAIRLYPKGDKGTEGQANKGRTPQ
YFVMKLPYSKVPRFIELPKHGKNYYLMFIEDIIKANIDTIFPGYDVDSSYCIKISRDADI
LIDESANTSEIIEQVKSKVKKRKIGAVCRFVYDRAMPDDFLDFLVDAFRINRQELVPGDK
HLNMEDLRHLPNPNNAVRPIRKPQPMKLTCLDERESIFRYVEKKDLLLHYPYHSFEHFIH
FLYEAVHEPTVREIMVTQYRVAENSAVINTLIAAAQNGKKVTVFVELKARFDEENNLATA
EMMKAAGINILFSLPGLKVHAKVALVLRRDRQGHKLPSYAYISTGNFNEKTATLYADSGL
FTCNPILVNDLHNLFRTFQGKENPVFHRLLVARFNLIPELNRLIDHEIELAKSGKQGRII
LKMNALQDPAMIDRLYEASQAGVRIDLIVRGICCLIPGRKYSRNIRVTRIVDTFLEHARV
WYFGNGGKPKLFLGSPDWMRRNLYRRIEAVTPILDPDLKRELSDMLSIQLSDKRKACFVD
DHLRNRWKSARPQKEKVRAQYTFYEYLKSGELRVES