Protein Info for HMPREF1181_RS06850 in Bacteroides stercoris CC31F

Annotation: putative DNA binding domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 557 PF04326: SLFN_AlbA_2" amino acids 27 to 143 (117 residues), 44.4 bits, see alignment E=2.3e-15 PF13749: HATPase_c_4" amino acids 334 to 399 (66 residues), 28.1 bits, see alignment E=1.7e-10

Best Hits

KEGG orthology group: K03655, ATP-dependent DNA helicase RecG [EC: 3.6.4.12] (inferred from 67% identity to bsa:Bacsa_1307)

Predicted SEED Role

"ATP-dependent DNA helicase RecG-related protein"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.12

Use Curated BLAST to search for 3.6.4.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (557 amino acids)

>HMPREF1181_RS06850 putative DNA binding domain-containing protein (Bacteroides stercoris CC31F)
MTSQELQQYLLREFPQENARCEWKEMKNLKNLFAGDEKNDVISYVAAIANMEGGHLVIGV
QDKTLEIVGTDLSKFNLNAQSAVWKLLEHCTNLSSEGLSIDEYTTEDSHKTVWIIHIPKH
LPRRPVYAHKKAWQRVEDSLVEMTQERLAAILEEPVFEAKDWSAEIVPNAVLTDLDELAV
AKARVMFKKVHASKIPAEEIDAWTVEELLSNSGIMIDGKLTRAAIILLGKPVSVFKLRPA
VVEVTWTLRDERQEVVDYEHFTAPFILTVDQILSKIRNLTMRELPGGTLFPETMKQYDDY
TIREALHNAIAHQDYTLQQRINFVENPGYLYYANGGSFIPGTLQNVLTTKGPQRYFRNEC
LCRAMVNFNMIDTVSRGIKKMFNEQWKRHFPMPDYEIDALNKEVGVKIYGNTINEKYTEL
LKENNTLTLGDCILLDAVQKRHRISEKDVVALLNRGLLEGDTSEYNISLDIAKKTRQLPY
YTHNRGLDKAKLQHMILQYLQNAGSVGAKRDAIFDYLRDVLPRNKTSEQQERMVGNILAE
MKEAEIVIVKGRIWYVK