Protein Info for HMPREF1181_RS06055 in Bacteroides stercoris CC31F

Annotation: GH92 family glycosyl hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 741 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details TIGR01180: putative alpha-1,2-mannosidase" amino acids 1 to 738 (738 residues), 838.4 bits, see alignment E=2.4e-256 PF17678: Glyco_hydro_92N" amino acids 35 to 262 (228 residues), 251.1 bits, see alignment E=1.4e-78 PF07971: Glyco_hydro_92" amino acids 268 to 734 (467 residues), 613.4 bits, see alignment E=3.2e-188

Best Hits

KEGG orthology group: None (inferred from 80% identity to bfs:BF0686)

MetaCyc: 80% identical to alpha-1,6-mannosidase (Bacteroides thetaiotaomicron)
3.2.1.-

Predicted SEED Role

"Alpha-1,2-mannosidase" in subsystem Mannose Metabolism

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (741 amino acids)

>HMPREF1181_RS06055 GH92 family glycosyl hydrolase (Bacteroides stercoris CC31F)
MKILRSICTVLPVLLLSSCMQRDALKVADECYADYVNPFIGTDFTGNTYPGAQVPFGMVQ
LSPDNGLPGWDRISGYFYPDSTIAGFSHTHLSGTGAGDLYDISFMPVTLPYKEAEEPLGI
HSRFSHADESASAGYYRVLLKDYDINVELTATERCGIQRYTFPQADAAVILNLRKAMNWD
FTEDSYVEKVDSVTIQGYRFSDGWARGQRIFFRTRFSRPFETMRLDSAAVLKDGKRIGTS
VMARFDFKTTKGEQLLVSTAISGVSMEGAARNLAAEVPDDDFDKYLAAARKNWNGHLSRI
EIECGNRDEKVKFYTALYHSMLAPTIYADVDGSYYGPDRQVHKADGWTNYSTFSLWDTYR
ASHPLYTYIEPARVNDMVKSFLAFYEQNGRLPVWNFYGSETDMMIGYHSVPVIVDACLKG
IGDFDAKKALEACVATANMDDYRGIGLYKKHGYVPYNVTDSYNAENWSLSKTLEYAYDDY
CIARLAEKLGERQVADEFYKRSQNYKNVYNPQTSFMQPRDDKGAFIDGFSPDDYTPHICE
SNGWQYFWSVQQDIDGLIALTGGKERFAQKLDSMFTYRPADDEELPIFSTGMIGQYAHGN
EPSHHVIYLFNKVGQPWKTQKYASEVMRELYKNTPAGLCGNEDCGQMSAWYVFSAMGFYP
VNPVGGEYEIGTPLYPEVRMRLSNGKTFTVLAHGVSGKNRYIRSVKLDGKPYDKSYIMHE
QIMNGSILEFEMGSEPGKAWY