Protein Info for HMPREF1181_RS05895 in Bacteroides stercoris CC31F

Annotation: Crp/Fnr family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 233 PF00027: cNMP_binding" amino acids 37 to 124 (88 residues), 59.8 bits, see alignment E=2.1e-20 PF13545: HTH_Crp_2" amino acids 156 to 229 (74 residues), 51.9 bits, see alignment E=5.8e-18

Best Hits

KEGG orthology group: None (inferred from 93% identity to bhl:Bache_1512)

Predicted SEED Role

"transcriptional regulator, Crp/Fnr family" in subsystem Oxidative stress

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (233 amino acids)

>HMPREF1181_RS05895 Crp/Fnr family transcriptional regulator (Bacteroides stercoris CC31F)
MVKINLSDINVPELIPDIWSPLNEEQREFLANHFTLQNYKKNEIIHCEGETPTCLMCLLN
GKVKIYKDGVGGRSQIIRMIKPTEYFGYRPYFAKADYVTAACAFEPSLVCLIPMTAIMTL
LSQNNELAMFFIRRLSIDLGIADERTVNLTQKHIRGRLAESLIFLKESYGLEEDGSTLSI
YLSREDLANLSNMTTSNAIRTLSQFAAERLITIDGRKIKIIDEEKLKKISKIG