Protein Info for HMPREF1181_RS05865 in Bacteroides stercoris CC31F
Annotation: DNA-3-methyladenine glycosylase I
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 53% identical to 3MG1_ECOLI: DNA-3-methyladenine glycosylase 1 (tag) from Escherichia coli (strain K12)
KEGG orthology group: K01246, DNA-3-methyladenine glycosylase I [EC: 3.2.2.20] (inferred from 87% identity to bvu:BVU_0852)MetaCyc: 53% identical to 3-methyl-adenine DNA glycosylase I, constitutive (Escherichia coli K-12 substr. MG1655)
DNA-3-methyladenine glycosylase I. [EC: 3.2.2.20]
Predicted SEED Role
"DNA-3-methyladenine glycosylase (EC 3.2.2.20)" in subsystem DNA Repair Base Excision (EC 3.2.2.20)
Isozymes
No predicted isozymesUse Curated BLAST to search for 3.2.2.20
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (194 amino acids)
>HMPREF1181_RS05865 DNA-3-methyladenine glycosylase I (Bacteroides stercoris CC31F) MQDIINGRCGWCGTDELYVKYHDEEWGRLVTDDRTLFEFLVLESSQAGLSWITILKKREG YRKAFCNFDAGQVAQMTDEDVERLMQFEGIVRNRLKIKSTITNARLFLAVQKEFGSFYNY TLSFFHDGKPIVNTVHSLSDIPVSSPQSDAMSKDMKKRGFKFFGSTICYAHLQAAGFVND HLAECICRQVKEEH