Protein Info for HMPREF1181_RS05520 in Bacteroides stercoris CC31F

Annotation: DUF4982 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 824 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF02837: Glyco_hydro_2_N" amino acids 31 to 190 (160 residues), 57.8 bits, see alignment E=4.2e-19 PF00703: Glyco_hydro_2" amino acids 203 to 300 (98 residues), 65.4 bits, see alignment E=2.3e-21 PF02836: Glyco_hydro_2_C" amino acids 305 to 515 (211 residues), 86.1 bits, see alignment E=7.4e-28 PF16355: DUF4982" amino acids 628 to 702 (75 residues), 76.7 bits, see alignment E=3.2e-25 PF18565: Glyco_hydro2_C5" amino acids 717 to 818 (102 residues), 113.9 bits, see alignment E=9.2e-37

Best Hits

KEGG orthology group: None (inferred from 82% identity to bsa:Bacsa_1984)

Predicted SEED Role

"Beta-galactosidase (EC 3.2.1.23)" in subsystem Galactosylceramide and Sulfatide metabolism or Lactose and Galactose Uptake and Utilization or Lactose utilization (EC 3.2.1.23)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.23

Use Curated BLAST to search for 3.2.1.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (824 amino acids)

>HMPREF1181_RS05520 DUF4982 domain-containing protein (Bacteroides stercoris CC31F)
MNKRLITGICCFFLFTAVMAQRTEVLLEKGWKFFRGDISGAAHPGYDDEQWQAVTVPHDW
AIYGPFDRDNDLQKVAVTQNFEKQASVKTGRTGGLPYVGVGWYRTTFTVPARKQATLVFD
GAMSEARVYINGQEACFWPFGYNSFHCDVTPYIYKDGKPNTLAVRLENKPQSSRWYPGAG
LYRNVRLLTTEPVCVPVWGTQLTTPHVSDKYASVRLRTEIANAGNKHIRIVTEIISPDGK
VVAAKDNTRKINHGQPFEQNFLVDAPALWSPETPRLYKASSKIYADGRLVDEYTTRFGIR
SIEIVADKGFFLNGKHRKFQGVCNHHDLGPLGAAVNVAALRRQLTLLKDMGCDAIRTSHN
MPAPELVELCDEMGFMMMIEPFDEWDIAKCDNGYHRYFDEWAERDMVNMLRHYRNNPSVV
MWSIGNEVPTQCSAEGYKVASFLQDICHREDPTRPVTCGMDQVSCVLENGFAAMIDVPGL
NYRAHRYVESYNALPQNIILGSETASTVSSRGVYKFPVEKRAGATYADHQSSGYDVEYCS
WSNVPDEDFALADDYDWTIGQFVWTGFDYLGEPSPYDTDAWPSHSSVFGIIDLASLPKDR
YYLYRSIWNKTANTLHVLPHWTWPGREGENTPVFVYTSYPAAELFVNGKSYGKQRKLTAS
ESKALQGKDSLALQRRYRLMWMDVPYEPGELKVVAYDASGKPAEEKIVRTAGKPHHLELV
ADRTRLAADGKDLAYITVRVVDKDGNLCQSDNRLVSFSVKGAGRYRAAANGDATSLDLFH
LPKMPAFSGQLTAIVQSTEQSGEIVFEAKAKGLQTGTILLSADR