Protein Info for HMPREF1181_RS04905 in Bacteroides stercoris CC31F

Annotation: DUF4421 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 365 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF14391: DUF4421" amino acids 53 to 354 (302 residues), 338.7 bits, see alignment E=1.9e-105

Best Hits

KEGG orthology group: None (inferred from 66% identity to bth:BT_1441)

Predicted SEED Role

"FIG00417980: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (365 amino acids)

>HMPREF1181_RS04905 DUF4421 domain-containing protein (Bacteroides stercoris CC31F)
MLRGICFCICMSVMLSLFAQNEESNFIAPDRTVHKRSEIIKRAIKKFLDFSDFDTAYISP
NRYNYALMLDHFTNYEYYSVGSGTPEPQRLRFSPKPHNKIGVYFGWRWLFLGWAVDADGL
YGKKNGKKRGREFDLSLYSSKLGVDIFYKRTGNSYKIHKITGFSDRIPTDYSEDFNGLKV
KMKGLNLYYIFNNRRFSYPAAFSQSTNQRRSAGSFITGFSVSAHNLDFDYTQLPPIIQET
MNPGMKVNHIKYTNISLNFGYAYNWVFARNCLACLSLNPAVAYKTSRIRKAEEETDEWYK
NFNIDFILRVGIVYNNSKYFAGTSFVGRTYDYYRNNFSLNNGFGTLQVYAGFNFCLKKEH
RKKKQ