Protein Info for HMPREF1181_RS04825 in Bacteroides stercoris CC31F

Annotation: aspartate-alanine antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 564 transmembrane" amino acids 12 to 29 (18 residues), see Phobius details amino acids 34 to 56 (23 residues), see Phobius details amino acids 62 to 81 (20 residues), see Phobius details amino acids 92 to 114 (23 residues), see Phobius details amino acids 157 to 177 (21 residues), see Phobius details amino acids 390 to 409 (20 residues), see Phobius details amino acids 415 to 433 (19 residues), see Phobius details amino acids 454 to 472 (19 residues), see Phobius details amino acids 478 to 501 (24 residues), see Phobius details amino acids 510 to 529 (20 residues), see Phobius details amino acids 541 to 563 (23 residues), see Phobius details TIGR03802: aspartate-alanine antiporter" amino acids 2 to 563 (562 residues), 711.2 bits, see alignment E=9.7e-218 PF06826: Asp-Al_Ex" amino acids 15 to 176 (162 residues), 132.8 bits, see alignment E=1.1e-42 amino acids 393 to 561 (169 residues), 163.3 bits, see alignment E=4.6e-52 TIGR01625: AspT/YidE/YbjL antiporter duplication domain" amino acids 21 to 167 (147 residues), 78.6 bits, see alignment E=4.4e-26 amino acids 398 to 547 (150 residues), 97.4 bits, see alignment E=7.1e-32 PF02080: TrkA_C" amino acids 318 to 379 (62 residues), 32.9 bits, see alignment E=4.8e-12

Best Hits

Swiss-Prot: 77% identical to Y1518_BACFR: Uncharacterized transporter BF1518 (BF1518) from Bacteroides fragilis (strain YCH46)

KEGG orthology group: None (inferred from 77% identity to bfr:BF1518)

Predicted SEED Role

"putative transport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (564 amino acids)

>HMPREF1181_RS04825 aspartate-alanine antiporter (Bacteroides stercoris CC31F)
MEWIFNQLRERPELAIFLTIFLGFWLGKLRIGKFTLGTVTSVLLVGVVVGQLNIAVPGPV
KSVFFLLFLFAVGYKVGPQFFRGLKKDGLPQVAFAVLMCVSVLGVTWLLALLMGYNMGEA
AGLLAGSQTISAVIGVAEDTMANMGLDEAQRQSYVNIIPVSYAVTYIFGTAGSAWVLSSI
GPKMLGGLDKVKAACKDLEVRMGNSQADEPGFIHAARPVTFRAYRIENEWFKNGKRVIDL
EVYFQQQDKRLFVERIRKAGAIREVSPNVQLEIGDEVVLSGRREYVIGEEDWIGPEIQDQ
QLLDFPAEKLPVMITKKTFAGKTVSAIRNEKFMHGVSIRSIRRAGIDIPVMAQTTVDAGD
VVEVVGTRQEVETAARRLGYIDRPTNQTDMIFVGLGILVGGLFGALSVHIGGVPISLSTS
GGALIAGLLFGWLRSKHPTFGRIPEPSQWVLNNVGLNMFIAVVGISAGPGFVQGFHDVGI
SLFLVGAAATTFPLIIGLLLARYLFKFHPAIALGCCAGARTTTAALGAIQDAVESETPAL
GYTVTYAVGNTLLIIWGVVIVLLI