Protein Info for HMPREF1181_RS04785 in Bacteroides stercoris CC31F

Annotation: Rne/Rng family ribonuclease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 524 TIGR00757: ribonuclease, Rne/Rng family" amino acids 14 to 438 (425 residues), 441.8 bits, see alignment E=1.2e-136 PF10150: RNase_E_G" amino acids 143 to 414 (272 residues), 325.7 bits, see alignment E=1.2e-101

Best Hits

KEGG orthology group: K08301, ribonuclease G [EC: 3.1.26.-] (inferred from 97% identity to bfr:BF1552)

Predicted SEED Role

"Cytoplasmic axial filament protein CafA and Ribonuclease G (EC 3.1.4.-)" in subsystem Bacterial Cell Division or RNA processing and degradation, bacterial (EC 3.1.4.-)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.26.- or 3.1.4.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (524 amino acids)

>HMPREF1181_RS04785 Rne/Rng family ribonuclease (Bacteroides stercoris CC31F)
MTSELVVDVQPKEVSIALLEDKSLVELQSEGRNISFSVGNMYLGRVKKLMPGLNACFVDV
GYEKDAFLHYLDLGPQFNSLEKYVKQTLSDKKKLNPITKATILPDLEKDGTVSNTLKVGQ
EVVVQIVKEPISTKGPRLTSELSFAGRYLVLIPFNDKVSVSQKIKSSEERARLKQLLMSI
KPKNFGVIVRTVAEGKRVAELDGELKVLLKHWEEAIVKVQKATKFPTLIYEETSRAVGLL
RDLFNPSFENIYVNNEAVFNEIKDYVTLIAPERAGIVKLYKGQLPIYDNFGITKQIKSSF
GKTVSYKSGAYLIIEHTEALHVVDVNSGNRIKNANGQEANALEVNLGAADELARQLRLRD
MGGIIVVDFIDMNEAENRQKLYERMCANMQKDRARHNILPLSKFGLMQITRQRVRPAMDV
NTTETCPTCFGKGTIKSSILFTDTLESKIDYLVNKLKIKKFSLHIHPYIAAYINQGVLSL
KRKWQMKYGFGIKIIPSQKLAFLEYVFYDPQGEEIDMKEEIEIK