Protein Info for HMPREF1181_RS04575 in Bacteroides stercoris CC31F
Annotation: multidrug efflux RND transporter permease subunit
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 92% identity to bth:BT_0305)Predicted SEED Role
"RND efflux system, inner membrane transporter CmeB" in subsystem Multidrug Resistance Efflux Pumps or Multidrug efflux pump in Campylobacter jejuni (CmeABC operon)
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (1036 amino acids)
>HMPREF1181_RS04575 multidrug efflux RND transporter permease subunit (Bacteroides stercoris CC31F) MKVSFFIDRPVFSAVISIVIVIVGIIGLTMLPVDQYPQITPPVVKISASYPGASALTVSQ AVATPIEQEINGTPGMLYMESNSSNSGGFSATVTFDVSADPDLAAVEIQNRIKLAESRLP AEVIQNGISVEKQAPSQLMTICLTSSDPKFDEIYLSNFATINVLDLLRRIPGVGRVSNIG SRYYAMQIWAMPDKLANFGLTVQDLQNALKDQNRESAAGVLGQQPVQGLDITIPITTQGR LSSAKQFEDIVVRANANGSIIRLRDVARVSLEASSYSTESGINGENAAVLGIYMLPGANA MEVADNVKKAMEEISANFPEGMSYEIPFDMTTYISESIHEVYKTLFEALVLVVLVVFLSL QSWRATLIPVVAVPISLIGTFGFMLIFGFSLNILTLLGLILAIGIVVDDAIVVVENVEHL METEKLSPYEATKKAMNGLASALIATSLVLCAVFVPVSFLSGITGQLYRQFTITIAVSVL LSTVVALTLSPVMCSLILKPDSGKKKNIVFRKINEWLNISNHKYIGVISRVIKHPRRLMS AFGMVLIAIFIIHRLIPTSFLPVEDQGYFKVELELPEGSTLERTRIVTDRAVQYLEQNPY VAYVQNVTGSSPRVGSNQARSELTVILKPWEERKNTTINKIMEKVEKDLREYPECRVYLS TPPVIPGLGTSGGFEMQLEARGEATFENLVQAADTLMYYAQKRKELTGLSSSLQSEIPQL YFDVDRDKVKMLGVPLADVFSTMKAYTGSVYVNDFNMFNRIYKVYIQAEAPYREHKENIN LFFVKAANGAMVPLTSLGNASYTTGPGSIKRFNMFTTAVILGSAAQGYSSGQAMEIMEQI AREHLPDNIGVEWSGLSYQEKKAGGQTGLVLTLVFLFVFLFLAAQYESWTVPIAVLLSLP VAALGAYLGVAVCGLENDIYFQIGLVMLVGLAAKNAILIVEFAKVQVDNGGDLVQSAIHA AQLRFRPILMTSLAFVLGMLPMVLASGPGSASRQAIGTGVFFGMIFAIVFGIVLVPFFFV LIYKAKEKVQHKIKKD