Protein Info for HMPREF1181_RS04450 in Bacteroides stercoris CC31F

Annotation: transketolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00456: Transketolase_N
  • amino acids 9 to 338 (330 residues), 311 bits, E=1.4e-96
• PF02779: Transket_pyr
  • amino acids 351 to 531 (181 residues), 136.6 bits, E=1.1e-43
• PF02780: Transketolase_C
  • amino acids 555 to 661 (107 residues), 26.9 bits, E=6e-10

Best Hits

KEGG orthology group: K00615, transketolase [EC: 2.2.1.1] (inferred from 92% identity to bhl:Bache_2866)

Predicted SEED Role

"Transketolase (EC 2.2.1.1)" in subsystem Calvin-Benson cycle or Pentose phosphate pathway (EC 2.2.1.1)

MetaCyc Pathways

• superpathway of glucose and xylose degradation (16/17 steps found)
• pentose phosphate pathway (8/8 steps found)
• pentose phosphate pathway (non-oxidative branch) II (6/6 steps found)
• pentose phosphate pathway (non-oxidative branch) I (5/5 steps found)
• formaldehyde assimilation III (dihydroxyacetone cycle) (10/12 steps found)
• Bifidobacterium shunt (12/15 steps found)
• pentose phosphate pathway (partial) (3/3 steps found)
• Rubisco shunt (8/10 steps found)
• formaldehyde assimilation II (assimilatory RuMP Cycle) (7/9 steps found)
• Calvin-Benson-Bassham cycle (9/13 steps found)
• ethene biosynthesis V (engineered) (15/25 steps found)
• oxygenic photosynthesis (9/17 steps found)
• 1-butanol autotrophic biosynthesis (engineered) (14/27 steps found)
• photosynthetic 3-hydroxybutanoate biosynthesis (engineered) (13/26 steps found)

KEGG Metabolic Maps

• Biosynthesis of alkaloids derived from shikimate pathway
• Biosynthesis of ansamycins
• Biosynthesis of phenylpropanoids
• Biosynthesis of plant hormones
• Carbon fixation in photosynthetic organisms
• Pentose phosphate pathway

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.2.1.1

Protein Sequence (669 amino acids)

>HMPREF1181_RS04450 transketolase (Bacteroides stercoris CC31F)
MNNKKLMNLAADNIRILAASMVEKANSGHPGGAMGGADFVNVLFSEFLVYDPENPAWEGR
DRFFLDPGHMSPMLYSTLALAGKFTLDELKEFRQWGSPTPGHPERDLMRGIENTSGPLGQ
GHTFAVGAAIAAKFMKARFEEVMNQTIYAYISDGGVQEEISQGAGRIAGALGLDNLIMFY
DANDIQLSTETKDVTIEDTAKKYEAWGWKVIKIDGNDADAIRGALNEAKAETERPTLIIG
HTVMGKGARKADGSSYEANCATHGAPLGGDAYVNTIKNLGGNPENPFTIFPEVAELYAKR
AAELKGIMAEKYAAKAAWAKANPEKAAKLELFFTGKAPEVDWAAIEQKANVATRAASATV
LGALATQVENMIVASADLSNSDKTDGFLKKTHSFKKGDFSGAFFQAGVSELTMACCCIGM
ALHGGVIPACGTFFVFSDYMKPAVRMAALMETPVKFIWTHDAFRVGEDGPTHEPVEQEAQ
IRLMEKLKNHKGHNSMLVLRPADAEETTVAWKLAMENVSTPTALIFSRQNITNLPAGNDY
SQAAKGAYIVAGSDENPDVILVASGSEVATLVAGAELLRKDGIKLRIVSVPSEGLFRSQA
PGYQESVIPANAKVFGLTAGLPVTLEGLVGAHGKVWGLESFGFSAPYKVLDEKLGFTAEN
VYKQVKAMI