Protein Info for HMPREF1181_RS04110 in Bacteroides stercoris CC31F

Annotation: ROK family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 402 PF13412: HTH_24" amino acids 18 to 61 (44 residues), 26.5 bits, see alignment 4e-10 PF00480: ROK" amino acids 89 to 397 (309 residues), 200.8 bits, see alignment E=3.5e-63

Best Hits

KEGG orthology group: None (inferred from 86% identity to bhl:Bache_2796)

Predicted SEED Role

"Mlc, transcriptional repressor of MalT (the transcriptional activator of maltose regulon) and manXYZ operon" in subsystem Maltose and Maltodextrin Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (402 amino acids)

>HMPREF1181_RS04110 ROK family transcriptional regulator (Bacteroides stercoris CC31F)
MAQELLKEIEMGSKNALIKKRIITHYIYNGSSTITDLSKELDLSVPTITKFIYEMCEDGY
INDYGKLETTGGRHPSLYGLNPESGYFIGVDIKKFSINIGLINFKGDMIELKMNIPYKFE
NTSEALEELCKLISNFIKKTGINTEKIMNICINISGRVNPDSGYSFSMFNFSERPLAEIL
TEKIGRPVCIDNDTRAMTYGEYMQGCVTGEKNIIFVNISWGLGIGIIIDGKIYTGKSGFS
GEFGHINVFENEILCHCGKKGCLETEASGSALHRILLERINSGENSILSNRINIKGDALT
LDEIIGAVNKEDLLCIEIVEEIGQKLGKQIAGLINIFNPELVIIGGTLSLTDDYIAQPIK
TAIRKYSLNLVNQDSAIMLSKLRDKAGIIGACMLARSRMFEC