Protein Info for HMPREF1181_RS04060 in Bacteroides stercoris CC31F

Annotation: molecular chaperone DnaJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 393 PF00226: DnaJ" amino acids 5 to 67 (63 residues), 94.8 bits, see alignment E=3.9e-31 TIGR02349: chaperone protein DnaJ" amino acids 5 to 369 (365 residues), 428 bits, see alignment E=1.7e-132 PF01556: DnaJ_C" amino acids 137 to 354 (218 residues), 150.2 bits, see alignment E=7e-48 PF00684: DnaJ_CXXCXGXG" amino acids 164 to 228 (65 residues), 62.5 bits, see alignment E=5.4e-21

Best Hits

Swiss-Prot: 89% identical to DNAJ_BACTN: Chaperone protein DnaJ (dnaJ) from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

KEGG orthology group: K03686, molecular chaperone DnaJ (inferred from 94% identity to bhl:Bache_2774)

Predicted SEED Role

"Chaperone protein DnaJ" in subsystem Heat shock dnaK gene cluster extended or Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (393 amino acids)

>HMPREF1181_RS04060 molecular chaperone DnaJ (Bacteroides stercoris CC31F)
MEKRDYYEVLEVEKTASAEEIKKAYRKKAIQYHPDKNPGDKVAEEKFKEAAEAYDVLSNP
DKRARYDQFGHAGMSGAAGNGGPFGGFSGGMSMDDIFSMFGDIFGGHSGGFGGGFSGFGG
FGGGGAQQQRRYRGSDLRVKVKLNLKEISTGVEKKFKLKKYVPCSHCHGTGAEGDGGAET
CPTCKGSGTVIRNQQTILGTMQTRTTCPTCGGEGKVIKNKCKECAGEGIVYGEEVVTVNI
PKGVAEGMQLSMGGKGNAGKHNGVPGDLLILVEEEQDKELIRDENDLIYNLLLSFPTAAL
GGAVEIPTIDGKVKVKIESGTQPGKVLRLRGKGLPNVNGYGTGDLLVNVSVYVPETLNKE
EKKALEEMEGSDNFKPNTSIKEKIFKKFKSLFD