Protein Info for HMPREF1181_RS03165 in Bacteroides stercoris CC31F

Annotation: TldD/PmbA family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 512 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF01523: PmbA_TldD_1st" amino acids 71 to 135 (65 residues), 54.9 bits, see alignment E=1.3e-18 PF19290: PmbA_TldD_2nd" amino acids 161 to 267 (107 residues), 66.9 bits, see alignment E=3.4e-22 PF19289: PmbA_TldD_3rd" amino acids 277 to 510 (234 residues), 219.7 bits, see alignment E=4.4e-69

Best Hits

KEGG orthology group: K03568, TldD protein (inferred from 88% identity to bhl:Bache_0365)

Predicted SEED Role

"TldD protein, part of TldE/TldD proteolytic complex"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (512 amino acids)

>HMPREF1181_RS03165 TldD/PmbA family protein (Bacteroides stercoris CC31F)
MDRRNFLRTGGMAVLGSLAMPSLAMPGSVRGALGGADSKSAVAAAANHFGVTEADLKKVM
AVALEKGGDYADLYFEHTFNNSVSLMDGKVNNCGSNIDFGMGVRVLSGDQSGYAYVEGVT
LEEMLRAARTAARIASSGRAGKPVGLTEKTIARSRYAVATPWEDVGVKEKIPYLEKLNEK
IFSLDNRVRKVQAYLQDSTSHVLFCNSEGVSYYDYRPMVSFMAVCIMEENGKMENGYAGR
SYRKGFEFMTDDVVDVIAREVVDRTAILFKAIKPKGGEMPVVMGSGGSGILLHEAIGHAF
EADFNRKDISIFAGQLNKKVCNEHINVVDDGTIPFNRGSVNFDDEGVEGQKTYIVKEGVL
TSYLHDRISAKHYGVNPTGNGRRDTFRNLPIPRMRATYMEAGNMKEADIISTVKNGIFVD
TFTNGQVQIGAGDFTFFVKSGYLIEDGKLTQPIKDINIIGNGPKALADITMVADNDKIDN
GTWTCGKDGQSCPVTCGMPSALVSKLTVGGEN