Protein Info for HMPREF1181_RS02815 in Bacteroides stercoris CC31F

Annotation: sulfatase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 522 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF00884: Sulfatase" amino acids 32 to 407 (376 residues), 172.9 bits, see alignment E=1.5e-54 PF16347: SGSH_C" amino acids 355 to 508 (154 residues), 247.7 bits, see alignment E=8.3e-78

Best Hits

Swiss-Prot: 51% identical to GLCSF_BACTN: N-acetylglucosamine-6-O-sulfatase (BT_4656) from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

KEGG orthology group: None (inferred from 77% identity to bvu:BVU_0538)

Predicted SEED Role

"Mucin-desulfating sulfatase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (522 amino acids)

>HMPREF1181_RS02815 sulfatase (Bacteroides stercoris CC31F)
MNKLQTGWLYTLTGAVSAVSLAACMPASKPYNIVYIMTDDHTAQMMSCYDNRYIETPNLD
RIANDGVRFVNSFVANSLSGPSRACMFTGKHTCGNKFYDNTTCVFDGSQQTFPKILRENG
YQTAVIGKWHLESLPTGFDYWEVVPGQGDYFNPDFITMNNDTVVRKGYITNLITDMSIDW
MENRRNKEKPFCLFIHHKAIHRNWLPEIKNLALYEDKTFPLPDNFYDDYKGRPAAASQEM
SIFKDMDLIYDLKMLKEGKDSPLKERYLSYIERMDADDRKAFDTFYAPIIEDFYKRDLKG
KELAEWKYQRYMRDYAKVVKSLDDNVGRVLDYLKEKDMLDNTLVVYTSDQGFYMGEHGWF
DKRFMYEESMHTPLIMHLPKGLDARGDITELVQNIDYGPTILDLAGISLPEDMHGISMLP
LLKGEHPVNWRKALYYHFYEYPAEHMVKRHYGVRTERYKLIHFYNDIDVWELYDLKNDPA
EMYNIYGQPGTEEVTAELKTTLLDLQQQYNDPVRFGPERDKE