Protein Info for HMPREF1181_RS02575 in Bacteroides stercoris CC31F

Annotation: transcription termination/antitermination protein NusA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 421 TIGR01953: transcription termination factor NusA" amino acids 10 to 348 (339 residues), 399.8 bits, see alignment E=4.5e-124 PF08529: NusA_N" amino acids 10 to 131 (122 residues), 116.9 bits, see alignment E=9e-38 PF13184: KH_5" amino acids 237 to 304 (68 residues), 100.1 bits, see alignment E=9e-33

Best Hits

KEGG orthology group: K02600, N utilization substance protein A (inferred from 97% identity to bth:BT_3403)

Predicted SEED Role

"Transcription termination protein NusA" in subsystem NusA-TFII Cluster or Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (421 amino acids)

>HMPREF1181_RS02575 transcription termination/antitermination protein NusA (Bacteroides stercoris CC31F)
MAKKEETISLIDTFSEFKELKNIDRTTMVSVLEESFRSVIAKMFGTDENYDVIVNPDKGD
FEIWRNREVVADEDLENPNLQISLSEARKIDASYEVGEEVTDEVNFAKFGRRAILNLRQT
LASKILELEKDSIYNKYIDKVGTIINAEVYQIWKKEMLLLDDEGNELLLPKTEQIPSDFY
RKGETARAVVARVDNKNNNPKIILSRTSPVFLQRLFEMEVPEINDGLITIKKIARIPGER
AKIAVESYDDRIDPVGACVGVKGSRIHGIVRELRNENIDVINYTSNIQLFIQRALSPAKI
SSIRLNEEEHKAEVFLKPEEVSLAIGKGGLNIKLASMLTEYTIDVFRELDEAVEDEDIYL
DEFRDEIDGWVIDAIKAIGIDTAKAVLNAPREMLIEKTDLEEETVDEVLRILKSEFEEGE
N