Protein Info for HMPREF1181_RS02120 in Bacteroides stercoris CC31F

Annotation: M20/M25/M40 family metallo-hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 334 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF04389: Peptidase_M28" amino acids 121 to 319 (199 residues), 168 bits, see alignment E=2.1e-53 PF01546: Peptidase_M20" amino acids 137 to 316 (180 residues), 31.7 bits, see alignment E=1.5e-11

Best Hits

KEGG orthology group: None (inferred from 85% identity to bhl:Bache_0645)

Predicted SEED Role

"Aminopeptidase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (334 amino acids)

>HMPREF1181_RS02120 M20/M25/M40 family metallo-hydrolase (Bacteroides stercoris CC31F)
MHKVFLGTACFLFSALSLHAQSPLEKGLQSINRTSAEAIVEFLADDELQGREAGMHGSRV
AARYIVSCLKEAGIRPLDKNGYYQPFEAYAKERQQRGRWQVHPDSVAVLKQGTHRSLKMD
NVLAYIPGKRSDEYVIVGAHFDHLGVDETLADDKIYNGADDNASGVSAVLQIARAFALSG
EKPLRNVIFAFWDGEEKGLLGSKHFVQHCPFLKQIKGYLNFDMIGRNNKPEQPQHVVYFY
TAAHPAFGEWLKRDITRYGLQLQPDYRPWDNPVGGSDNASFARSDIPVIWYHTDGHPDYH
QPSDHAALLNWEKVVEITKASFLNAWNLANESNY