Protein Info for HMPREF1181_RS01180 in Bacteroides stercoris CC31F

Annotation: translational GTPase TypA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 599 PF00009: GTP_EFTU" amino acids 3 to 194 (192 residues), 189.9 bits, see alignment E=8.9e-60 TIGR00231: small GTP-binding protein domain" amino acids 3 to 142 (140 residues), 74.9 bits, see alignment E=6.5e-25 TIGR01394: GTP-binding protein TypA/BipA" amino acids 4 to 595 (592 residues), 917.5 bits, see alignment E=3e-280 PF01926: MMR_HSR1" amino acids 8 to 128 (121 residues), 22.6 bits, see alignment E=2.4e-08 PF03144: GTP_EFTU_D2" amino acids 217 to 287 (71 residues), 48 bits, see alignment E=3.5e-16 PF00679: EFG_C" amino acids 396 to 478 (83 residues), 79.6 bits, see alignment E=3.7e-26 PF21018: BipA_C" amino acids 481 to 589 (109 residues), 157 bits, see alignment E=3.4e-50

Best Hits

Swiss-Prot: 51% identical to TYPA_BACSU: GTP-binding protein TypA/BipA homolog (typA) from Bacillus subtilis (strain 168)

KEGG orthology group: K06207, GTP-binding protein (inferred from 93% identity to bhl:Bache_0912)

Predicted SEED Role

"GTP-binding protein TypA/BipA" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (599 amino acids)

>HMPREF1181_RS01180 translational GTPase TypA (Bacteroides stercoris CC31F)
MQNIRNIAIIAHVDHGKTTLVDKMLLAGNLFRSNQSTGELMLDNNDLERERGITILSKNV
SISYKDTKINIIDTPGHSDFGGEVERVLNMADGCILLVDAFEGPMPQTRFVLQKALQIGL
KPIVVVNKVDKPNCRPEEVYEMVFDLMFSLEATEEQLDFPVIYGSAKNNWMSTDWQKPTD
NIYPLLDCILENIPAPTQLEGTPQMLVTSLDYSSYTGRIAVGRVHRGTLREGMNVSLAKR
DGTIVKSKIKELHTFEGMGRVKVSEVSSGDICALVGIEGFEIGDTICDYENPEALPPIAI
DEPTMSMLFTINDSPFFGKEGKFVTSRHIHDRLMKELDKNLALRVRKSEEDGKWVVSGRG
VLHLSVLIETMRREGYELQVGQPQVIFKEIDGVKNEPIEELTVNVPEEYASKIIDMVTRR
KGEMVKMESAGERVNLEFNMPSRGIIGLRTNVLTASAGEAIMAHRFKEYQPYKGEIERRT
NGSIIAMESGTAFAYAIDKLQDRGKFFIFPQEEVYAGQVVGEHSHDNDLVVNVTKSKKLT
NMRASGSDEKARLIPPVQFSLEEALEYIKGDEYVEVTPKSMRMRKVILDETERKRANKN