Protein Info for HMPREF1181_RS01060 in Bacteroides stercoris CC31F

Annotation: RNA polymerase sigma-70 factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 198 transmembrane" amino acids 182 to 197 (16 residues), see Phobius details PF07638: Sigma70_ECF" amino acids 7 to 170 (164 residues), 21.8 bits, see alignment E=2.3e-08 TIGR02985: RNA polymerase sigma-70 factor, Bacteroides expansion family 1" amino acids 17 to 181 (165 residues), 158.8 bits, see alignment E=1.4e-50 TIGR02937: RNA polymerase sigma factor, sigma-70 family" amino acids 18 to 180 (163 residues), 80.8 bits, see alignment E=8.6e-27 PF04542: Sigma70_r2" amino acids 21 to 86 (66 residues), 50.8 bits, see alignment E=1.8e-17 PF08281: Sigma70_r4_2" amino acids 125 to 177 (53 residues), 53.2 bits, see alignment E=2.7e-18

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (198 amino acids)

>HMPREF1181_RS01060 RNA polymerase sigma-70 factor (Bacteroides stercoris CC31F)
MEERMFFSKIQQGDTASFEWLYKRYHPRMYMFCKGILHDEDKAKDLVQECFIAFWEHRTQ
INAPEAISVYLFRIMKHLCLKQIRRDSLLNNFSNMNEVALRELELSHYTPECNILNDLYF
KDLSEKYQEALDKLPRQCQNIFRMNRNEGMRSEEIAIALNLSVRTVENQLYRGLKQIKKS
MQDYLPVLLLLLVKNFLK