Protein Info for HMPREF1181_RS00995 in Bacteroides stercoris CC31F

Annotation: TolC family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 422 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF02321: OEP" amino acids 29 to 213 (185 residues), 59.4 bits, see alignment E=2.2e-20 amino acids 241 to 346 (106 residues), 54.3 bits, see alignment E=7.7e-19

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (422 amino acids)

>HMPREF1181_RS00995 TolC family protein (Bacteroides stercoris CC31F)
MFMIRLLLIVFISFIGVSVPARQIRLSSDQIEAMFLKQNLALIAERMNVSIADAAIAEAT
VWDNPELSVGDINFWKRRGTDEYGGAVASPKQFSLELSQMVSLSARRIKLAEVEKIDKEI
TVRQFEELLRSLKMELHISIAELVYLQNLLKVIESRQTLLEKVVAGYRAQYQTGNVTGNE
LLRLQTALFAVNGEMNEVRTEYNAHQKNIKNLLALEPSVVVIVAEEQVDFPSPLTLDPAM
LMETALASRPDLAAAVLRAEYHRKDIVYQKALAIPDISLGVKYDRAGGVWDNFFGVGIGV
QLPVFNRNKGAIRSARFRLRQNEILVLQERNNIRNEIIECLENYKAVYSFLEENGVNRSI
QSEMDKMPDVYTKNLLMKNISMVEYMDFMDSYHASKEVLLRSRKELRLQFERLQFAIGQT
IK