Protein Info for HMPREF1181_RS00635 in Bacteroides stercoris CC31F

Annotation: aminopeptidase P family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 597 PF01321: Creatinase_N" amino acids 8 to 134 (127 residues), 70.4 bits, see alignment E=4.3e-23 PF16189: Creatinase_N_2" amino acids 151 to 308 (158 residues), 186.5 bits, see alignment E=7.4e-59 PF00557: Peptidase_M24" amino acids 312 to 522 (211 residues), 159.7 bits, see alignment E=1.8e-50 PF16188: Peptidase_M24_C" amino acids 533 to 593 (61 residues), 95.2 bits, see alignment E=3.6e-31

Best Hits

KEGG orthology group: K01262, Xaa-Pro aminopeptidase [EC: 3.4.11.9] (inferred from 75% identity to bhl:Bache_1038)

Predicted SEED Role

"Xaa-Pro aminopeptidase (EC 3.4.11.9)" (EC 3.4.11.9)

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.9

Use Curated BLAST to search for 3.4.11.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (597 amino acids)

>HMPREF1181_RS00635 aminopeptidase P family protein (Bacteroides stercoris CC31F)
MNLIINERIAALRTHIAQENIQAFIIPSTDPHLSEYVAPHWQSREWISGFTGSAGTVVIT
AEEAGLWTDSRYFLQAARQIEGTEITLYKEMLPETPSIPAFLNSRLQEGDTVGIDGKMFS
AKEVEHLQEALRKSGIHVKSVADPLQLLWKDRPTMPLSPAFIHDTQYAGRSFTEKLAAVR
KEMDANGAESLLLSALDEIAWLLNIRGNDVHCNPVVVSYLLIEKNAVHYFIQPQKVTAEL
TAYFNVNGISVHTYEEIEDYLNHLPARSILADSAKTNYAIYSAINPQCRIIDGTSPVTLL
KAIRNKQEIAGIHTAMQRDGVALVKFLKWLEDAVPTGRETEISIDRKLHAFRAAQPLYMG
ESFDTIAGYKEHGAIVHYEATPETDVTLKAEGFLLLDSGAQYLDGTTDITRTIALGNLTE
EEKTDYTLILKGHIALATAVFPEGTRGAQLDVLARLPIWKQHMNYLHGTGHGVGHFLNVH
EGPQSIRMNENPIPLQPGMVTSNEPGVYKAGSHGIRTENLLLTVPAGEGMFGNYLKFETV
TLCPICRKGIIKELLTAEEIEWLNEYHRVVYEKLSPDLENDEKEWLKEACKPLIINR