Protein Info for HMPREF1181_RS00535 in Bacteroides stercoris CC31F

Annotation: elongation factor G

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 705 TIGR00484: translation elongation factor G" amino acids 4 to 699 (696 residues), 1041.4 bits, see alignment E=0 PF00009: GTP_EFTU" amino acids 9 to 284 (276 residues), 204.1 bits, see alignment E=3.8e-64 TIGR00231: small GTP-binding protein domain" amino acids 9 to 183 (175 residues), 107.3 bits, see alignment E=6.8e-35 PF03144: GTP_EFTU_D2" amino acids 327 to 394 (68 residues), 67.5 bits, see alignment E=2.8e-22 PF14492: EFG_III" amino acids 407 to 480 (74 residues), 114.8 bits, see alignment E=3.8e-37 PF03764: EFG_IV" amino acids 482 to 603 (122 residues), 138.5 bits, see alignment E=2.3e-44 PF00679: EFG_C" amino acids 606 to 692 (87 residues), 96.3 bits, see alignment E=2.2e-31

Best Hits

Swiss-Prot: 98% identical to EFG_BACFR: Elongation factor G (fusA) from Bacteroides fragilis (strain YCH46)

KEGG orthology group: K02355, elongation factor G (inferred from 98% identity to bhl:Bache_1054)

Predicted SEED Role

"Translation elongation factor G" in subsystem Translation elongation factor G family or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (705 amino acids)

>HMPREF1181_RS00535 elongation factor G (Bacteroides stercoris CC31F)
MAKNDLHLTRNIGIMAHIDAGKTTTSERILFYTGLTHKIGEVHDGAATMDWMEQEQERGI
TITSAATTTRWKYAGNTYKINLIDTPGHVDFTAEVERSLRILDGAVAAYCAVGGVEPQSE
TVWRQADKYNVPRIAYVNKMDRSGADFFEVVRQMKDVLGANPCPIVVPIGAEESFKGLVD
LIKMKAIYWHDETMGADYTVEEIPANLVDEANEWRDKMLEKVAEFDDALMEKYFDDPSTI
TEEEILRALRNATVQMAVVPMLCGSSFKNKGVQTLLDYVCAFLPSPLDTENVVGTNPETG
AEEDRKPSEDEKTSALAFKIATDPYVGRLTFFRVYSGKIEAGSYIYNSRSGKKERVSRLF
QMHSNKQNPVEVIGAGDIGAGVGFKDIHTGDTLCDETAPIVLESMDFPEPVIGIAVEPKT
QKDMDKLSNGLAKLAEEDPTFTVKTDEQTGQTVISGMGELHLDIIIDRLKREFKVECNQG
KPQVNYKEAITKTVNLREVYKKQSGGRGKFADIIVNIGPVDEDFTQGGLQFVDEVKGGNI
PKEFIPSVQKGFTTAMKNGVLAGYPLDSLKVTLIDGSFHPVDSDQLSFEICAIQAYKNAC
AKAGPVLMEPIMKLEVVTPEENMGDVIGDLNKRRGQVEGMESSRSGARIVKAMVPLAEMF
GYVTALRTITSGRATSSMAYSHHAQVSNSIAKAVLEEVKGRTDLI