Protein Info for HMPREF1181_RS00100 in Bacteroides stercoris CC31F

Annotation: U32 family peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 622 PF01136: Peptidase_U32" amino acids 78 to 305 (228 residues), 256.2 bits, see alignment E=2.4e-80 PF12392: DUF3656" amino acids 383 to 509 (127 residues), 65 bits, see alignment E=9.6e-22

Best Hits

Predicted SEED Role

"Putative collagenase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (622 amino acids)

>HMPREF1181_RS00100 U32 family peptidase (Bacteroides stercoris CC31F)
MMKQRKIELLAPAKNLECGIEAVNHGADAVYIGAPKFGARAAAVNSLEDIAALVAYAHLY
NVRIYVTVNTILKEEELAETEKMIWELYRIGVDALIVQDMGITRLNLPSIPLHGSTQMDN
RTPEKVRFLADAGFRQVVLARELSLQEIRRIHETCPETPLEVFVHGALCVSYSGQCYVSQ
ACFGRSANRGECAQFCRLPFSLVDADGKTIVRDKHLLSLKDLNQSEVLEDLLDAGASSLK
IEGRLKDVSYVKNVTAAYRSKLDAIFARRKEYVRASSGTCRFDFTPRLDKSFSRGFTHYF
LQGRDREISSFDTPKSLGEEMGTMKEQRGNYLTVAGVKPFHNGDGVCFLDEQGRLQGFRI
NRVDGNKLYPAGDVPRIKPRTRLFRNFDQEFERILARKSAERKIGVGWELADTPSGFALT
AADEDGNRITLSFPYPKELARTPQPENLRTQLGKLGNTPFEVMPLGGTDSPSATTAPAIA
INLSQNWFIPASVIADWRRQAIDKLTAARRITYRRELHVWKPTRHRFPATSLTYLGNVMN
TAARSFYQAHGVASVEPAYEKQAVPEAVLMFCKHCLRYSMGWCPTHQKGHSPYREPYYLV
GTDGKRFRLTFDCKNCQMKVSG