Protein Info for HGI48_RS21690 in Dickeya dianthicola 67-19

Annotation: restriction endonuclease subunit S

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 502 PF01420: Methylase_S" amino acids 163 to 328 (166 residues), 56.2 bits, see alignment E=2.7e-19

Best Hits

Predicted SEED Role

"Type I restriction-modification system, specificity subunit S (EC 3.1.21.3)" in subsystem Restriction-Modification System (EC 3.1.21.3)

Isozymes

Compare fitness of predicted isozymes for: 3.1.21.3

Use Curated BLAST to search for 3.1.21.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RJV1 at UniProt or InterPro

Protein Sequence (502 amino acids)

>HGI48_RS21690 restriction endonuclease subunit S (Dickeya dianthicola 67-19)
MKHGLVDQAYKFKKRVASSDTSNYRIAYKNELVVGFPIDEGVLGFQTKYPAGIVSPAYDI
WKLKNETACHIPYLERYLRSSEARSLYASRMQGAVARRRSLTKTDFLSLEVPFPLLDDQI
RIAHLLGKVEALITQRKHHLQQLDDLLKSVFLEMFGDPVRNEKGWDKPELKAFGKISTGN
TPPRNEPANYDGNFIEWIKTDNITGDAVFVTPSTEHLSEVGARKARTVTNGALLVACIAG
SIESIGRAALTDRTVSFNQQINAIQPGKDIEPLYLYGLFKLSRAYIQNHATKGMKKILTK
GDFEKITMIKPPFEIQNQFATIVEKVESIKSRYQQSLADLEALYSSLSQRAFKGELDLSR
VPLPDQPVADVSIEEYAAEPEMVVQTEPAIHLPATDNLSATLENAEARKALMARWLEAYR
TQLDGTPFSAQQFITVAQARLAELHPDHDIALGASDYENIKAWVFEQVRARRLKQTRDII
LINNKRQFGNRLLLRARRQPDQ