Protein Info for HGI48_RS21625 in Dickeya dianthicola 67-19

Annotation: UDP-4-amino-4-deoxy-L-arabinose aminotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 380 PF01041: DegT_DnrJ_EryC1" amino acids 12 to 373 (362 residues), 447.9 bits, see alignment E=7.6e-138 PF01053: Cys_Met_Meta_PP" amino acids 32 to 216 (185 residues), 38 bits, see alignment E=2e-13 PF01212: Beta_elim_lyase" amino acids 33 to 275 (243 residues), 31.5 bits, see alignment E=2.9e-11 PF00155: Aminotran_1_2" amino acids 35 to 163 (129 residues), 38 bits, see alignment E=3e-13 PF05889: SepSecS" amino acids 42 to 159 (118 residues), 21.9 bits, see alignment E=1.7e-08

Best Hits

Swiss-Prot: 78% identical to ARNB_KLEP3: UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase (arnB) from Klebsiella pneumoniae (strain 342)

KEGG orthology group: K07806, UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase [EC: 2.6.1.87] (inferred from 98% identity to ddd:Dda3937_01080)

MetaCyc: 77% identical to UDP-4-amino-4-deoxy-L-arabinose aminotransferase (Escherichia coli K-12 substr. MG1655)
RXN0-1863 [EC: 2.6.1.87, 2.6.1.92]

Predicted SEED Role

"UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase (EC 2.6.1.-)" in subsystem Lipid A-Ara4N pathway ( Polymyxin resistance ) (EC 2.6.1.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.-

Use Curated BLAST to search for 2.6.1.- or 2.6.1.87 or 2.6.1.92

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RJJ7 at UniProt or InterPro

Protein Sequence (380 amino acids)

>HGI48_RS21625 UDP-4-amino-4-deoxy-L-arabinose aminotransferase (Dickeya dianthicola 67-19)
MADFLPFSRPALGEEELAAVGQVLRSGWITTGPKNQELEQQFAVLTGAKHAIAVSSATGG
MHVTLMALGIGAGDEVITPSLTWVSTLNMIVLLGAEPVMVDVDRDNLMVTPQAIEAAITP
RTKAIIPVHYAGAPADIDAIRDIGRRHGIPVIDDAAHAAGTYYRGRHVGGEGTAIFSFHA
IKNMTCAEGGLVVTDDDALANRIRSLKFHGLAVDAFDRMVQGRAPQAEVVSPGFKYNLPD
ISAAIALVQLEKLAANNARREALAQRYLRKLAALPFQPLTLPSWPHQHAWHLFIIRVDEA
RCGIDRDGLMQALKDRNIGTGLHFRAAHTQKYYRERFTNLHLPNTDWNSARICSLPLFPD
MHDEDVDRVVDALTELAGTC