Protein Info for HGI48_RS21500 in Dickeya dianthicola 67-19

Annotation: thioesterase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13279: 4HBT_2
  • amino acids 17 to 120 (104 residues), 56.9 bits, E=2.9e-19
• PF03061: 4HBT
  • amino acids 25 to 94 (70 residues), 33.9 bits, E=3.3e-12

Best Hits

KEGG orthology group: K07107, acyl-CoA thioester hydrolase [EC: 3.1.2.-] (inferred from 94% identity to ddc:Dd586_4174)

Predicted SEED Role

"FIG002571: 4-hydroxybenzoyl-CoA thioesterase domain protein"

KEGG Metabolic Maps

• Benzoate degradation via CoA ligation
• Biosynthesis of plant hormones
• Biosynthesis of unsaturated fatty acids
• Fatty acid biosynthesis
• Limonene and pinene degradation
• Ubiquinone and menaquinone biosynthesis
• alpha-Linolenic acid metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.1.2.-

Use Curated BLAST to search for 3.1.2.-

Sequence Analysis Tools

See A0A7L9RIY1 at UniProt or InterPro

Protein Sequence (142 amino acids)

>HGI48_RS21500 thioesterase family protein (Dickeya dianthicola 67-19)
MSALTDRDLSHEVELVVSFHDCDPMGVVWHGNYFRFFEVAREALLGKYHYGYREMKASGY
VWPVVDTRVKYRSVLTYEQRIRVRATIEEVENRLRIAYQIFDTQSGQRTTTGYTIQVAVE
EGSKTLSFVSPQILLDRLGVTV