Protein Info for HGI48_RS21070 in Dickeya dianthicola 67-19

Annotation: ROK family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 367 signal peptide" amino acids 20 to 22 (3 residues), see Phobius details transmembrane" amino acids 23 to 41 (19 residues), see Phobius details PF00480: ROK" amino acids 88 to 242 (155 residues), 91.1 bits, see alignment E=9.5e-30

Best Hits

KEGG orthology group: None (inferred from 94% identity to dze:Dd1591_4127)

Predicted SEED Role

"N-acetyl-D-glucosamine kinase (EC 2.7.1.59)" (EC 2.7.1.59)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.59

Use Curated BLAST to search for 2.7.1.59

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RIQ4 at UniProt or InterPro

Protein Sequence (367 amino acids)

>HGI48_RS21070 ROK family transcriptional regulator (Dickeya dianthicola 67-19)
MEKRELTATHRKLLGLLRRSGSLSRSALAAASGLTTAAVSMMTRDMLNLGLLEESDRAQG
RRGPPQINLRPAAHAGYVLGIYAEYDLICLILMDYAGQCVAQTTLRGDFRVVDSVADTLA
GAIRPLLDAQPQARGRLLAVSLALPARFDGGAMPVWIAPGLAAWRGVDIARQLSDRLGCP
VLVENDANCAAIGELNFGSAAPDDSFFYLYIGKGIGGALILNGELHRGKQGNAGEIGALR
TRAQSRPSFDDLYDYLLAADEPLPSTADDANWQALAASPAGKRWTQRAAGELYRLLYTVT
ALLDPPSLYLGGTLPAPFMAGLQAAVMAQTPAPDDDAPLTLPPVRLSTLPTQNSAAFGAA
ALALNQY