Protein Info for HGI48_RS20210 in Dickeya dianthicola 67-19

Annotation: UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 357 transmembrane" amino acids 6 to 23 (18 residues), see Phobius details amino acids 43 to 61 (19 residues), see Phobius details amino acids 67 to 84 (18 residues), see Phobius details amino acids 96 to 117 (22 residues), see Phobius details amino acids 127 to 148 (22 residues), see Phobius details amino acids 156 to 175 (20 residues), see Phobius details amino acids 181 to 198 (18 residues), see Phobius details amino acids 210 to 228 (19 residues), see Phobius details amino acids 240 to 259 (20 residues), see Phobius details amino acids 290 to 310 (21 residues), see Phobius details amino acids 316 to 334 (19 residues), see Phobius details TIGR02380: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase" amino acids 4 to 345 (342 residues), 477.8 bits, see alignment E=9.7e-148 PF00953: Glycos_transf_4" amino acids 70 to 229 (160 residues), 101.9 bits, see alignment E=1.9e-33

Best Hits

Swiss-Prot: 67% identical to WECA_YERPE: Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase (wecA) from Yersinia pestis

KEGG orthology group: K02851, undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase [EC: 2.7.8.-] (inferred from 94% identity to ddd:Dda3937_00268)

MetaCyc: 63% identical to UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase (Escherichia coli O157)
GLCNACPTRANS-RXN [EC: 2.7.8.33]

Predicted SEED Role

"Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-)" in subsystem Methicillin resistance in Staphylococci or Teichoic and lipoteichoic acids biosynthesis (EC 2.7.8.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.8.-

Use Curated BLAST to search for 2.7.8.- or 2.7.8.33

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RIA9 at UniProt or InterPro

Protein Sequence (357 amino acids)

>HGI48_RS20210 UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase (Dickeya dianthicola 67-19)
MSAQLVAVFLCSFFSLLLARNVARKTGLVDRPNYRKRHHGAVPLVGGISVYIGVCLLPVL
ISESIPHFPIYLMCSGMLVLIGALDDRFDLSIGVRAAVQAVVAILMMALAGLVLQRLGYI
LGPLWDIGLGPMSYFMTLFVVWTAINAFNMVDGIDGLLGGLSCVLFAGLGILLYHHGSLA
LALWSFAMIAAILPYILLNLELMGRRYKVFMGDAGSTMIGFTAIWLLLQSSQGSDSAIRP
VAALWVIAIPLMDMVAIVYRRLHKGTGLFSPDRQHIHHLLMRAGLASRQACLLITLAAVL
LAAVGIAGELLAVPEYVMLALFLLAFSGYGYCIKRAWRVARVVRRIQRYWRSHRYCE