Protein Info for HGI48_RS19950 in Dickeya dianthicola 67-19

Annotation: pirin family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 232 PF02678: Pirin" amino acids 8 to 119 (112 residues), 131.3 bits, see alignment E=1.5e-42 PF17954: Pirin_C_2" amino acids 143 to 228 (86 residues), 102.2 bits, see alignment E=1.5e-33

Best Hits

Swiss-Prot: 77% identical to YHHW_ECOLI: Quercetin 2,3-dioxygenase (yhhW) from Escherichia coli (strain K12)

KEGG orthology group: K06911, (no description) (inferred from 98% identity to ddd:Dda3937_00320)

MetaCyc: 77% identical to quercetin 2,3-dioxygenase (Escherichia coli K-12 substr. MG1655)
Quercetin 2,3-dioxygenase. [EC: 1.13.11.24]

Predicted SEED Role

"Qercetin 2,3-dioxygenase"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.13.11.24

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RI52 at UniProt or InterPro

Protein Sequence (232 amino acids)

>HGI48_RS19950 pirin family protein (Dickeya dianthicola 67-19)
MIYLRKAQDRGHANHGWLDSWHTFSFADYYDPDFMGFSALRVINEDRIEGGQGFGTHPHR
DMEILTYVLQGSVEHQDSMGNKEQIPAGEFQIMSAGTGIRHSEYNASQDELLHLYQIWVI
PEKTGLTPRYEQRRFDARQGRQLVLSPDARDGSLKVFQDMTLWRWALKSQEESVYQTQQG
RHLWIQVVRGTIEINGQQATASDALAIWDEDSITVRAGEDSEILLFDLPPVK