Protein Info for HGI48_RS19890 in Dickeya dianthicola 67-19

Annotation: gluconate transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 438 signal peptide" amino acids 6 to 14 (9 residues), see Phobius details transmembrane" amino acids 15 to 18 (4 residues), see Phobius details amino acids 20 to 40 (21 residues), see Phobius details amino acids 54 to 76 (23 residues), see Phobius details amino acids 97 to 126 (30 residues), see Phobius details amino acids 136 to 154 (19 residues), see Phobius details amino acids 174 to 196 (23 residues), see Phobius details amino acids 221 to 242 (22 residues), see Phobius details amino acids 262 to 279 (18 residues), see Phobius details amino acids 295 to 316 (22 residues), see Phobius details amino acids 337 to 393 (57 residues), see Phobius details amino acids 415 to 437 (23 residues), see Phobius details PF02447: GntP_permease" amino acids 1 to 436 (436 residues), 602.1 bits, see alignment E=5.8e-185 TIGR00791: transporter, gluconate:H+ symporter (GntP) family" amino acids 1 to 438 (438 residues), 642.8 bits, see alignment E=1.5e-197 PF03600: CitMHS" amino acids 14 to 384 (371 residues), 64.9 bits, see alignment E=7.3e-22

Best Hits

Swiss-Prot: 83% identical to GNTT_ECOLI: High-affinity gluconate transporter (gntT) from Escherichia coli (strain K12)

KEGG orthology group: K06155, Gnt-I system high-affinity gluconate transporter (inferred from 97% identity to ddc:Dd586_3847)

MetaCyc: 83% identical to high-affinity gluconate transporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-209

Predicted SEED Role

"High-affinity gluconate transporter GntT" in subsystem D-gluconate and ketogluconates metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CUR0 at UniProt or InterPro

Protein Sequence (438 amino acids)

>HGI48_RS19890 gluconate transporter (Dickeya dianthicola 67-19)
MPLVIVAVGVALLLVLMIRFKLNGFIALILVALAVGIMQGMPVQKVMTSIKNGVGGTLGS
LALIMGFGAMLGKLLADCGGAQRIATTLIHRFGRKHIQWAIVLTGFTVGFALFYEVGFVL
LLPLVFSIVASARIPLLYAGVPMAAALSVTHGFLPPHPGPTAIASLFHADMGKTLLYGTL
LGIPTVILAGPVFARFLKKIDKPIPEGLYNPKQFTEQEMPSFFVSVMTALVPVILMALRA
VAEMVLPKGHALLPYAEFFGDPVMATLIAVLIAIFTFGLNRGRSMDEVMGTITDSIKIIA
MMLLILGGGGAFKQVLVDSGVDKYIAGMMYGSNFSPLLLGWLIAAVLRLALGSATVAALT
AGGIVAPIIATTGVSPELMVIAVGSGSVIFSHVNDPGFWLFKEYFNLSIPETLKSWSALE
TIIAVCGLVGTLLLSYVV