Protein Info for HGI48_RS19840 in Dickeya dianthicola 67-19

Annotation: glycogen synthase GlgA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 477 TIGR02095: glycogen/starch synthase, ADP-glucose type" amino acids 1 to 476 (476 residues), 567.3 bits, see alignment E=1.3e-174 PF08323: Glyco_transf_5" amino acids 2 to 233 (232 residues), 250.8 bits, see alignment E=4.1e-78 PF13579: Glyco_trans_4_4" amino acids 17 to 219 (203 residues), 36.5 bits, see alignment E=1.6e-12 PF13439: Glyco_transf_4" amino acids 106 to 221 (116 residues), 37.5 bits, see alignment E=6.2e-13 PF00534: Glycos_transf_1" amino acids 289 to 439 (151 residues), 43.2 bits, see alignment E=7.9e-15 PF13692: Glyco_trans_1_4" amino acids 293 to 438 (146 residues), 32 bits, see alignment E=3.5e-11

Best Hits

Swiss-Prot: 86% identical to GLGA_PECCP: Glycogen synthase (glgA) from Pectobacterium carotovorum subsp. carotovorum (strain PC1)

KEGG orthology group: K00703, starch synthase [EC: 2.4.1.21] (inferred from 98% identity to ddd:Dda3937_00333)

MetaCyc: 77% identical to glycogen synthase (Escherichia coli K-12 substr. MG1655)
Starch synthase. [EC: 2.4.1.21]

Predicted SEED Role

"Glycogen synthase, ADP-glucose transglucosylase (EC 2.4.1.21)" in subsystem Glycogen metabolism (EC 2.4.1.21)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RI47 at UniProt or InterPro

Protein Sequence (477 amino acids)

>HGI48_RS19840 glycogen synthase GlgA (Dickeya dianthicola 67-19)
MRVLHVCSELFPLLKTGGLADVVGALPSAQIAAGMDVRVLLPAYPDLKKGIPDAQVVREL
DTFGGRVTLRYGHYNGVGIYLIDVPHLYERAGSPYHDTSLFAYSDNFLRFGLLGWMGAEM
ASGVDPFWRPDIVHAHDWHAGLTCAYLAAKGRPAKSVFTVHNLAYQGLFDARHLSELRLP
PEYFSMYGLEFYGQLSYLKAGLYYADHITTVSPTYAHEITQTEYGYGLEGLLKSREEDGR
LSGILNGVDDEIWNPAHDSLLTATYSRDELARKADNKRHLQTAMGLKVDDRVPVFAIVSR
LTSQKGLDIALQTVPGLLEQGGQLVVLGAGDATLQEGFLAAAAEYHGRVGVQIGYHEAFS
HRIIGGADVIMVPSRFEPCGLTQLYGLKYGTLPLVRRTGGLADTVADCSLENLADGLASG
FVFSDCNTASLSRAIRRVFVLWSRPSLWRYVQRQAMAMDFSWQVAAQAYRALYQRLW