Protein Info for HGI48_RS17940 in Dickeya dianthicola 67-19

Annotation: secA regulator SecM

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 166 signal peptide" amino acids 1 to 39 (39 residues), see Phobius details PF06558: SecM" amino acids 24 to 165 (142 residues), 183.9 bits, see alignment E=8.5e-59

Best Hits

Swiss-Prot: 52% identical to SECM_CITK8: Secretion monitor (secM) from Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)

KEGG orthology group: K13301, secretion monitor (inferred from 92% identity to ddd:Dda3937_02234)

Predicted SEED Role

"Secretion monitor precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RH54 at UniProt or InterPro

Protein Sequence (166 amino acids)

>HGI48_RS17940 secA regulator SecM (Dickeya dianthicola 67-19)
MIGILNRWRQFGRRYFWPHLLLGMVAATLGLPANFTESRDASSAPNSASAISRPNVSYFN
LTDLAALKDSRRRSPFSNDFWHQHAIRTVIRHLSFAFTPPVTVVEATEASRLHHQVLLET
LNALLTREATPPTSACADLVPSHFSPSHHSGLWLAQVQGIRAGPRV