Protein Info for HGI48_RS17900 in Dickeya dianthicola 67-19

Annotation: type II secretion system protein GspE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 491 transmembrane" amino acids 341 to 359 (19 residues), see Phobius details PF00437: T2SSE" amino acids 101 to 366 (266 residues), 325.9 bits, see alignment E=8.2e-102

Best Hits

KEGG orthology group: K02504, protein transport protein HofB (inferred from 92% identity to ddd:Dda3937_02242)

Predicted SEED Role

"Type IV fimbrial assembly, ATPase PilB" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RHJ0 at UniProt or InterPro

Protein Sequence (491 amino acids)

>HGI48_RS17900 type II secretion system protein GspE (Dickeya dianthicola 67-19)
MTHNALQHELQLLCRRYHALLLDMDEQVVSIAVAGLVAEELIAALRFASHRRVLVEQWPA
ARLEQQLTSPQAEETIAPYQVAATALDEPDDAPVVQFINQTLKLAIQRRASDIHFEPLPA
GYRVRLRIDGVLHETPPAPDSLAGRLIARLKIMGKLNIAERRLPQDGQFSLRLDQHAYSL
RIATLPVQGGEKVVLRVLQTQQQALELDALGLPARALQQFKQALSLPQGLILVTGPTGSG
KTFTLYSAIRWLNDVSRNICSVEDPIEIPLAGINQTAIHAPSQLDFARVLRALLRQDPDV
IMIGEIRDAETAEIAVKAAQTGHLVLSTLHTNSAADTLVRLGHLGIPGYLLAAALKLVIA
QRLVRRLCPHCRQLTEDAVTLPDNLWQGPLRQWRATGCEHCFSGYYGRAAIYELLPVTPA
LQQALSGSAALSGSALSVSGSALSGSASWSDNSQPLPLQRGTGLLSSGLVLVHEGITSLE
EVYRVVGDRIE