Protein Info for HGI48_RS17440 in Dickeya dianthicola 67-19

Annotation: PTS sugar transporter subunit IIC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 448 transmembrane" amino acids 25 to 51 (27 residues), see Phobius details amino acids 73 to 95 (23 residues), see Phobius details amino acids 106 to 128 (23 residues), see Phobius details amino acids 148 to 166 (19 residues), see Phobius details amino acids 186 to 208 (23 residues), see Phobius details amino acids 232 to 253 (22 residues), see Phobius details amino acids 265 to 281 (17 residues), see Phobius details amino acids 295 to 315 (21 residues), see Phobius details amino acids 351 to 371 (21 residues), see Phobius details amino acids 393 to 419 (27 residues), see Phobius details TIGR00410: PTS system, lactose/cellobiose family IIC component" amino acids 14 to 431 (418 residues), 359.5 bits, see alignment E=1.3e-111 PF02378: PTS_EIIC" amino acids 29 to 360 (332 residues), 167.2 bits, see alignment E=2.6e-53

Best Hits

KEGG orthology group: K02761, PTS system, cellobiose-specific IIC component (inferred from 98% identity to ddc:Dd586_3408)

Predicted SEED Role

"PTS system, cellobiose-specific IIC component (EC 2.7.1.69)" in subsystem Beta-Glucoside Metabolism (EC 2.7.1.69)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RGV7 at UniProt or InterPro

Protein Sequence (448 amino acids)

>HGI48_RS17440 PTS sugar transporter subunit IIC (Dickeya dianthicola 67-19)
MSFKDKAIDSLGSFANQFNSLRYIMAIKASFITLMPVIIVGAFSVLISNMVLDPRNGLAS
FAMFSFLAPLKPIMSGINYATLNFLTIGAVFLIGIELGRINGSRGLFPGLLAVICFISIT
PTTIDMVINGQTLPVKDVLARQFSDTKSLFLGMFIAIASVEIYSKLESVDRLRIKMPDSV
PPNVSASFSALIPAIITVTLVATFGFTFQKATGMYLYDAIYMVVQQPLESVVQSLPGLLI
LMFVAQLFWVIGIHGNQMIKPIREPLLLGAIAVNMTAFEQGHDVPNIITMPFWDVYMSIG
GSGLTIGLLLAVMIASKRREMKEIAKISFGPGVFNINEPVIFGMPIMLNPILAIPFIITP
LVTGTIGYFATSMGFAGKAVVMVPWTTPPIINAWLSTAGSMGAVATQVVCIIVATLIYLP
FVKVASRRAEQAQREAESDAAAQANALK