Protein Info for HGI48_RS17340 in Dickeya dianthicola 67-19

Annotation: type IV pilus twitching motility protein PilT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 342 TIGR01420: twitching motility protein" amino acids 3 to 332 (330 residues), 449 bits, see alignment E=5.8e-139 PF00437: T2SSE" amino acids 11 to 270 (260 residues), 147.5 bits, see alignment E=4.3e-47 PF01580: FtsK_SpoIIIE" amino acids 114 to 149 (36 residues), 24.6 bits, see alignment 1.6e-09

Best Hits

Swiss-Prot: 64% identical to YGGR_ECOLI: Uncharacterized protein YggR (yggR) from Escherichia coli (strain K12)

KEGG orthology group: K02669, twitching motility protein PilT (inferred from 95% identity to ddd:Dda3937_02602)

Predicted SEED Role

"Twitching motility protein PilT" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RGW4 at UniProt or InterPro

Protein Sequence (342 amino acids)

>HGI48_RS17340 type IV pilus twitching motility protein PilT (Dickeya dianthicola 67-19)
MDVSEWVRSSVKQNVSDLHLCSGHPPVWRIDGQLVADAAQPPLHNAELEQWCRSWLDPAC
ERQLRQSGQTDCALTLPEGQRLRANLFMQRHGLSAALRLIPQHQPDLPTLGAPPVVAELA
DCADGLILVTGATGSGKSTTLAAMITALNQRRARHIITLEDPIEFLHTSRRSLIQQREIG
RHSEGFASALRAALREDPDVLLLGELRDGETIRLALTAAETGHLVLATLHTRRAVQAVDR
LVDVFPAEEKAFVRAQLAASLQAVVAQKLLPGAQGGRVALFEVLLATPAVSNLIREGKTH
QLPSLLQTGSQVGMQTFEQSYQQRCREGALRPDADAAGMVSA