Protein Info for HGI48_RS17080 in Dickeya dianthicola 67-19

Annotation: two-component sensor histidine kinase BarA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 921 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 44 to 60 (17 residues), see Phobius details amino acids 174 to 196 (23 residues), see Phobius details PF09984: sCache_4" amino acids 31 to 174 (144 residues), 161.8 bits, see alignment E=3.4e-51 PF00672: HAMP" amino acids 196 to 245 (50 residues), 31.9 bits, see alignment 4.8e-11 PF00512: HisKA" amino acids 290 to 354 (65 residues), 78.2 bits, see alignment 1.4e-25 PF02518: HATPase_c" amino acids 401 to 515 (115 residues), 99.8 bits, see alignment E=4.4e-32 PF00072: Response_reg" amino acids 672 to 782 (111 residues), 94.7 bits, see alignment E=1.4e-30 PF01627: Hpt" amino acids 828 to 907 (80 residues), 44.7 bits, see alignment E=4.5e-15

Best Hits

KEGG orthology group: None (inferred from 96% identity to ddd:Dda3937_00193)

Predicted SEED Role

"BarA sensory histidine kinase (= VarS = GacS)" in subsystem Type III secretion system orphans

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RH72 at UniProt or InterPro

Protein Sequence (921 amino acids)

>HGI48_RS17080 two-component sensor histidine kinase BarA (Dickeya dianthicola 67-19)
MTKYSLRARMMILILAPAMLIGLLLSSFFVIHRYNQLQEQLADAGASIIQPLAVNSAYAL
TQRQPESLRQLVNMLHRHHSGIVRTISVFDARNQLIVTSNPNNPHGQLLQVPSGNPLPTA
LRMQNEGECLVLQMPIENEGDVSASTLISRQAPMGYVAVELDLNTIRLQQYREMFMAAML
LLFCMGVAMLLAYRLMRDVTIPIRNMVETVDRIRRGQLDSRVEGHMLGELDMLKNGINSM
AMSLTAYHEEMQQNIDQATYDLRETLEQMEIQNVELDLAKKRAQEAARIKSEFLANMSHE
LRTPLNGVIGFTRQTLKTQLTSTQKDYLQTIERSANNLLNIINDVLDFSKLEAGKLVLEN
IPFSLHNTLDEVIMLLAHTAHEKGLELTLNIQHDVPEQFVGDPLRLQQIITNLLGNAIKF
TEQGNIDIRIEKRRQESVQVLLEIQIKDTGIGIAEAQQTQLFQAFRQADTSISRQHGGTG
LGLVITQRLVREMGGDISFHSKLNQGTTFWCTVNLQLNPHVLEPDYHFARLQGKHLAYVE
ANPAAAQATLDILVHTPLTVSYSPTLEQLPERTFDILLIGIPIHYRNTLLDFTPLIRDFC
RLASCVILALPSMAEMEAEQLKSFGIHASLSKPITAPRLLTMLQDNNLFSQDGNERALPP
PAVSLSLLPLSVMAVDDNPANLKLIGALLEEQVENIILCESGADAIARAQGAHLDIILMD
IQMPGMDGLQASEHIRQLPQHAHTPIVAVTAHTMSGEREALLQSGMDDYLSKPIDEQMLR
QTLLRHACKTPSSLPALPSPAVTAQSPLSLDWDLALRQAASKPDLARDLLAMLLDFLPDV
RQQVSAVLAGNPPGNMVDIIHKLHGSCSYSGVPRLKQICHYLEQSLRKGLPVDELEPEWL
ELMDEMTNVERAARKRLETSA