Protein Info for HGI48_RS16420 in Dickeya dianthicola 67-19

Annotation: phophatidylserine decarboxylase associated domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF12588: PSDC
  • amino acids 73 to 218 (146 residues), 109.2 bits, E=1.8e-35
• PF02666: PS_Dcarbxylase
  • amino acids 239 to 438 (200 residues), 89 bits, E=3.4e-29

Best Hits

KEGG orthology group: K01613, phosphatidylserine decarboxylase [EC: 4.1.1.65] (inferred from 97% identity to dze:Dd1591_0966)

Predicted SEED Role

"FIG00613581: hypothetical protein"

MetaCyc Pathways

• superpathway of phospholipid biosynthesis III (E. coli) (11/12 steps found)
• superpathway of cardiolipin biosynthesis (bacteria) (10/13 steps found)
• phosphatidylserine and phosphatidylethanolamine biosynthesis I (2/2 steps found)
• cardiolipin and phosphatidylethanolamine biosynthesis (Xanthomonas) (3/4 steps found)
• superpathway of phospholipid biosynthesis II (plants) (10/28 steps found)

KEGG Metabolic Maps

• Glycerophospholipid metabolism

Isozymes

Compare fitness of predicted isozymes for: 4.1.1.65

Use Curated BLAST to search for 4.1.1.65

Sequence Analysis Tools

See A0A7L9RGM6 at UniProt or InterPro

Protein Sequence (474 amino acids)

>HGI48_RS16420 phophatidylserine decarboxylase associated domain-containing protein (Dickeya dianthicola 67-19)
MTHTKSHTASTPEAEPSPHYESSGHSLLTLDNAGPIQMGFWVPNRVWATAKFLIPLREHI
ANKKQANTLTPMQPVLQNVKNWVTNHSVYRMWLNSMIEQSNAYVASLPESTRKEISDDGD
VIWIDDYDSFFEILNEIITTSPSFNTTAQVGTPMNAFLAVAMGTEAGVALFHDATFNQQF
RQVLDAWNSFLKSSASLDKLDIAQPEKPGSWIAKGAYQAGVWHQMQHDPNLPGYGFASWN
DFFIRQFVPGARPFQGDPNTQVDIGCETTPWRHADQLQLESRFWVKDIPYSLLDLFGGQR
QWAKLFEGGQLYQGFLSATHYHRWNAPLDGFLVRSWVEPGTYFAQRPGQGEDQGTWEGTE
SQPYLGHVAARAVFIFRHKTCGYVALICIGMVEVSSCVIEPSTFIVEESAEPVGITRGVE
IGHFEFGGSTHMMIFQKDRVALEKWAIDAARHRNDQNPVPLGSVIATALDSKGQ