Protein Info for HGI48_RS15845 in Dickeya dianthicola 67-19

Annotation: anti-sigma-E factor RseA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 221 transmembrane" amino acids 98 to 120 (23 residues), see Phobius details PF03872: RseA_N" amino acids 1 to 87 (87 residues), 120.7 bits, see alignment E=3.2e-39 PF03873: RseA_C" amino acids 136 to 190 (55 residues), 77.7 bits, see alignment E=6.4e-26

Best Hits

Swiss-Prot: 58% identical to RSEA_SALT1: Anti-sigma-E factor RseA (rseA) from Salmonella typhimurium (strain 14028s / SGSC 2262)

KEGG orthology group: K03597, sigma-E factor negative regulatory protein RseA (inferred from 97% identity to ddd:Dda3937_03845)

Predicted SEED Role

"Sigma factor RpoE negative regulatory protein RseA" in subsystem Transcription initiation, bacterial sigma factors

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RG76 at UniProt or InterPro

Protein Sequence (221 amino acids)

>HGI48_RS15845 anti-sigma-E factor RseA (Dickeya dianthicola 67-19)
MQKEKLSALMDGEAVDNALLGALSKDDKLQQSWQRYHLVRDTLRGDVSETLMNIDIAARV
AAALEQEPVQFNPQAVPESQPHPRTWQMLPFWRKVRPLASHLTQIGMAACVSLAVIVGVQ
HYQQNNAMSDSVAETAPALSTLPVMGGSASPVSLSVPAENSVAHTGQRQMQAQHERINAL
LQDYELQRRVHSDQLQLQQQGSQQQAAVQVPGTQSLGIQPQ