Protein Info for HGI48_RS15030 in Dickeya dianthicola 67-19

Annotation: extracellular solute-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 417 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF01547: SBP_bac_1" amino acids 41 to 324 (284 residues), 104.9 bits, see alignment E=8.7e-34 PF13416: SBP_bac_8" amino acids 45 to 353 (309 residues), 157.8 bits, see alignment E=5.2e-50

Best Hits

Swiss-Prot: 49% identical to CYCB_BACSU: Cyclodextrin-binding protein (cycB) from Bacillus subtilis (strain 168)

KEGG orthology group: K10108, maltose/maltodextrin transport system substrate-binding protein (inferred from 96% identity to ddd:Dda3937_02389)

Predicted SEED Role

"Maltose/maltodextrin ABC transporter, substrate binding periplasmic protein MalE" in subsystem Bacterial Chemotaxis or Maltose and Maltodextrin Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RG36 at UniProt or InterPro

Protein Sequence (417 amino acids)

>HGI48_RS15030 extracellular solute-binding protein (Dickeya dianthicola 67-19)
MKTKTLTALLLCATAAGQLAAFPVHAAQQLTVWEDIRKSDGIKDAIRDFEKQYNVSVNLQ
EMPYAQQLEKLRLDGPAGIGPDVLVIPNDQLGGAVVQGLIAPLKLDQAVQDSFTEASMAA
FRMNNQVYGLPKAVETLVLIYNKEQVSKPLASLQEWYDFSRRQQAQNTFGLLAKFDQIYY
SWGAIGPMGGYIFGKNDKDFGKNDKGGLNPLDIGLNTPGAVEAVTLLRKFYADKLFPAGI
IGDNGLNAIDSLFTEKKAAAVINGPWAFQPYEAAGIHYGVAPLPLLPDGKPMSSFLGVKG
YVVSTWSKDNALAQRFIDFINQPRYVKVRYQRTGEIPPQKSMIDDPLIKNDEKASAVAIQ
AARAVPMPGIPEMGEVWGPANAALELSMTGKQQPKAALDNAVKQIKMQVEAMQASNQ