Protein Info for HGI48_RS14725 in Dickeya dianthicola 67-19

Annotation: type II secretion system inner membrane protein GspF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 408 transmembrane" amino acids 172 to 195 (24 residues), see Phobius details amino acids 226 to 245 (20 residues), see Phobius details amino acids 374 to 400 (27 residues), see Phobius details TIGR02120: type II secretion system protein F" amino acids 4 to 405 (402 residues), 532.9 bits, see alignment E=3e-164 PF00482: T2SSF" amino acids 74 to 196 (123 residues), 122.1 bits, see alignment E=7.2e-40 amino acids 277 to 398 (122 residues), 94.4 bits, see alignment E=2.7e-31

Best Hits

Swiss-Prot: 83% identical to GSPF_PECCC: Type II secretion system protein F (outF) from Pectobacterium carotovorum subsp. carotovorum

KEGG orthology group: K02455, general secretion pathway protein F (inferred from 99% identity to ddd:Dda3937_02417)

MetaCyc: 51% identical to type II secretion system protein GspF (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"General secretion pathway protein F"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CRP3 at UniProt or InterPro

Protein Sequence (408 amino acids)

>HGI48_RS14725 type II secretion system inner membrane protein GspF (Dickeya dianthicola 67-19)
MALFQYQALNAQGKKSQGMQEADSARHARQLLREKGLVPVKIEEQRGEVTSRSGFSLSLR
RSHRISASDLALLTRQLATLVAAALPLEEALDAVAKQSEKPKLSALMAAVRAKVVEGHSL
AEAMGNFPGSFERLYCAMVAAGEASGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT
LVAISVVSILLSAVVPKVVEQFIHMKQALPLSTRLLMGVSDAVRSYGPWVVVLLVLAVMG
FRVLLRQEKHRLVFHRRLLFLPLIGRIARGLNTARYARTLSILNSSAVPLLQAMRISGDV
LTNDYARFRLGQATDAVREGVSLNKALEQTSLFPPMMRHMIASGERSGELDGMLTRAADN
QDREFSAQMTLALGLFEPLLVVSMAGIVLFIVLAILQPILQLNTLMSM