Protein Info for HGI48_RS14690 in Dickeya dianthicola 67-19

Annotation: type II secretion system protein M

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 162 signal peptide" amino acids 1 to 44 (44 residues), see Phobius details PF04612: T2SSM" amino acids 1 to 160 (160 residues), 134 bits, see alignment E=2.8e-43

Best Hits

Swiss-Prot: 58% identical to GSPM_PECCC: Type II secretion system protein M (outM) from Pectobacterium carotovorum subsp. carotovorum

KEGG orthology group: K02462, general secretion pathway protein M (inferred from 97% identity to ddd:Dda3937_02424)

Predicted SEED Role

"General secretion pathway protein M"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A7L9RFS1 at UniProt or InterPro

Protein Sequence (162 amino acids)

>HGI48_RS14690 type II secretion system protein M (Dickeya dianthicola 67-19)
MNELRRRWQIMSQRERMMTLACGGLVLLCLLYYLCWVPWQEWARQWQMTIDRERQTVRWM
QQQAPRLPPTEGARRQIAGRDTSLTVLVPQSASRYGITVLRMQPQESQVSVTLARSDFNN
LLHWLAELEQKNGVITQGLDVTAVPNSAGMVEVTRLSLERVL